Exosomes Derived from Adipose Tissue-Derived Mesenchymal Stromal Cells Prevent Medication-Related Osteonecrosis of the Jaw through IL-1RA

Exosomes Derived from Adipose Tissue-Derived Mesenchymal Stromal Cells Prevent Medication-Related Osteonecrosis of the Jaw through IL-1RA

Medication-related osteonecrosis of the jaw (MRONJ) is a severe disease with unclear pathogenesis. Adipose tissue-derived mesenchymal stromal cells (MSC(AT)s) serve as a special source for cell therapy. Herein, we explored whether exosomes (Exo) derived from MSC(AT)s promote primary gingival wound h...

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Bibliographic Details
Main Authors: Yi Zheng, Xian Dong, Xinyu Wang, Jie Wang, Shuo Chen, Yang He, Jingang An, Linhai He, Yi Zhang
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:International Journal of Molecular Sciences
Subjects:
medication-related osteonecrosis of the jaw
zoledronate
adipose tissue-derived mesenchymal stromal cells
exosomes
interleukin-1 receptor antagonist
human gingival fibroblasts
Online Access:https://www.mdpi.com/1422-0067/24/10/8694

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https://www.mdpi.com/1422-0067/24/10/8694

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