Exosomes Derived from Adipose Tissue-Derived Mesenchymal Stromal Cells Prevent Medication-Related Osteonecrosis of the Jaw through IL-1RA

Exosomes Derived from Adipose Tissue-Derived Mesenchymal Stromal Cells Prevent Medication-Related Osteonecrosis of the Jaw through IL-1RA

Medication-related osteonecrosis of the jaw (MRONJ) is a severe disease with unclear pathogenesis. Adipose tissue-derived mesenchymal stromal cells (MSC(AT)s) serve as a special source for cell therapy. Herein, we explored whether exosomes (Exo) derived from MSC(AT)s promote primary gingival wound h...

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Bibliographic Details
Main Authors:	Yi Zheng, Xian Dong, Xinyu Wang, Jie Wang, Shuo Chen, Yang He, Jingang An, Linhai He, Yi Zhang
Format:	Article
Language:	English
Published:	MDPI AG 2023-05-01
Series:	International Journal of Molecular Sciences
Subjects:	medication-related osteonecrosis of the jaw zoledronate adipose tissue-derived mesenchymal stromal cells exosomes interleukin-1 receptor antagonist human gingival fibroblasts
Online Access:	https://www.mdpi.com/1422-0067/24/10/8694

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