Secondary prevention of early-onset sepsis: a less invasive Italian approach for managing neonates at risk

Abstract Strategies to prevent early-onset sepsis (EOS) have led to a substantial decline in many countries. However, one of the most controversial topics in neonatology is the management of asymptomatic full-term and late preterm neonates at risk for EOS, and guidelines lack substantial consensus r...

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Main Authors: Alberto Berardi, Chryssoula Tzialla, Laura Travan, Jenny Bua, Daniele Santori, Milena Azzalli, Caterina Spada, Laura Lucaccioni, on behalf of the GBS Prevention Working Group of Emilia-Romagna
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Italian Journal of Pediatrics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13052-018-0515-8
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author Alberto Berardi
Chryssoula Tzialla
Laura Travan
Jenny Bua
Daniele Santori
Milena Azzalli
Caterina Spada
Laura Lucaccioni
on behalf of the GBS Prevention Working Group of Emilia-Romagna
author_facet Alberto Berardi
Chryssoula Tzialla
Laura Travan
Jenny Bua
Daniele Santori
Milena Azzalli
Caterina Spada
Laura Lucaccioni
on behalf of the GBS Prevention Working Group of Emilia-Romagna
author_sort Alberto Berardi
collection DOAJ
description Abstract Strategies to prevent early-onset sepsis (EOS) have led to a substantial decline in many countries. However, one of the most controversial topics in neonatology is the management of asymptomatic full-term and late preterm neonates at risk for EOS, and guidelines lack substantial consensus regarding this issue. A strategy for managing neonates, entirely based on serial physical examinations, has been developed in two Italian regions. This strategy seems safe, while reducing laboratory tests and unnecessary antibiotics. In the current commentary we provide area-based data concerning the prevention of EOS in 2 northern Italian regions, and we detail the results of their strategy for managing healthy-appearing newborns at risk for EOS.
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spelling doaj.art-014e841a5ee044d5bf38b7c1960904dc2022-12-22T03:04:22ZengBMCItalian Journal of Pediatrics1824-72882018-06-014411410.1186/s13052-018-0515-8Secondary prevention of early-onset sepsis: a less invasive Italian approach for managing neonates at riskAlberto Berardi0Chryssoula Tzialla1Laura Travan2Jenny Bua3Daniele Santori4Milena Azzalli5Caterina Spada6Laura Lucaccioni7on behalf of the GBS Prevention Working Group of Emilia-RomagnaUnità Operativa di Terapia Intensiva Neonatale, Dipartimento Integrato Materno-Infantile, Azienda Ospedaliero-Universitaria PoliclinicoNeonatologia, Patologia Neonatale e Terapia Intensiva Neonatale, Fondazione IRCCS Policlinico “San Matteo”Unità Operativa di Terapia Intensiva Neonatale, IRCCS “Burlo Garofolo”Unità Operativa di Terapia Intensiva Neonatale, IRCCS “Burlo Garofolo”Struttura Complessa di Pediatria e Neonatologia, Azienda Ospedaliera Santa Maria degli AngeliUnità Operativa di Terapia Intensiva Neonatale, Ospedale S. AnnaScuola di specializzazione in Pediatria, Università di Modena e Reggio Emilia, Azienda Ospedaliero-Universitaria PoliclinicoUnità Operativa di Terapia Intensiva Neonatale, Dipartimento Integrato Materno-Infantile, Azienda Ospedaliero-Universitaria PoliclinicoAbstract Strategies to prevent early-onset sepsis (EOS) have led to a substantial decline in many countries. However, one of the most controversial topics in neonatology is the management of asymptomatic full-term and late preterm neonates at risk for EOS, and guidelines lack substantial consensus regarding this issue. A strategy for managing neonates, entirely based on serial physical examinations, has been developed in two Italian regions. This strategy seems safe, while reducing laboratory tests and unnecessary antibiotics. In the current commentary we provide area-based data concerning the prevention of EOS in 2 northern Italian regions, and we detail the results of their strategy for managing healthy-appearing newborns at risk for EOS.http://link.springer.com/article/10.1186/s13052-018-0515-8Group B streptococcusNeonatal sepsisIntrapartum antibiotic prophylaxisNewborn infantRisk factorsPrevention
spellingShingle Alberto Berardi
Chryssoula Tzialla
Laura Travan
Jenny Bua
Daniele Santori
Milena Azzalli
Caterina Spada
Laura Lucaccioni
on behalf of the GBS Prevention Working Group of Emilia-Romagna
Secondary prevention of early-onset sepsis: a less invasive Italian approach for managing neonates at risk
Italian Journal of Pediatrics
Group B streptococcus
Neonatal sepsis
Intrapartum antibiotic prophylaxis
Newborn infant
Risk factors
Prevention
title Secondary prevention of early-onset sepsis: a less invasive Italian approach for managing neonates at risk
title_full Secondary prevention of early-onset sepsis: a less invasive Italian approach for managing neonates at risk
title_fullStr Secondary prevention of early-onset sepsis: a less invasive Italian approach for managing neonates at risk
title_full_unstemmed Secondary prevention of early-onset sepsis: a less invasive Italian approach for managing neonates at risk
title_short Secondary prevention of early-onset sepsis: a less invasive Italian approach for managing neonates at risk
title_sort secondary prevention of early onset sepsis a less invasive italian approach for managing neonates at risk
topic Group B streptococcus
Neonatal sepsis
Intrapartum antibiotic prophylaxis
Newborn infant
Risk factors
Prevention
url http://link.springer.com/article/10.1186/s13052-018-0515-8
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