Examination of Age Related Volume Changes in Brain by Magnetic Resonance Imaging Method
Aim: Normal brain aging is accompanied by cognitive decline. Determination of age-related changes in the brain helps in understanding the healthy aging process. Our aim was to examine the volume changes occurring due to advanced age by investigating the age-related changes in brain during normal agi...
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| Format: | Article |
| Language: | English |
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Istanbul Gelisim University Press
2018-08-01
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| Series: | İstanbul Gelişim Üniversitesi Sağlık Bilimleri Dergisi |
| Subjects: | |
| Online Access: | https://dergipark.org.tr/tr/pub/igusabder/issue/38973/401823 |
| _version_ | 1797912234598334464 |
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| author | Tuncay Varol Ceyda Hayretdağ Örs Necip Ozan Tiryakioğlu |
| author_facet | Tuncay Varol Ceyda Hayretdağ Örs Necip Ozan Tiryakioğlu |
| author_sort | Tuncay Varol |
| collection | DOAJ |
| description | Aim: Normal brain aging is
accompanied by cognitive decline. Determination of age-related changes in the
brain helps in understanding the healthy aging process. Our aim was to examine
the volume changes occurring due to advanced age by investigating the age-related
changes in brain during normal aging process.
Method: This study was carried out on
the magnetic resonance (MR) images of 29 healthy subjects consisting of 13
males and 16 females between the ages of 20 to 80. Volumes of right and left
cerebral hemispheres, right and left frontal lobes, and right and left temporal
lobes were measured by Cavalieri sections method on MR images.
Findings: A significant age-related
decline in the volumes of all investigated regions (p<0.05) was observed.
The decline in volume is higher in males in comparison to females.
Additionally, it has been observed that in male subjects, the volume of right
hemisphere, right frontal lobe and right temporal lobe showed more signs of
atrophy than left side; whereas in females, the volume of right frontal lobe
showed a more prominent decline than its left frontal lobe.
Conclusion: An age-related decline in
brain volume has been detected for both sexes; however male subjects suffered a
more prominent decline than females. We believe that the reason behind this
more significant decline might be the effect of gonodal hormones. |
| first_indexed | 2024-04-10T11:53:17Z |
| format | Article |
| id | doaj.art-01501b507bfd4ef3867cb3228836eec5 |
| institution | Directory Open Access Journal |
| issn | 2536-4499 2602-2605 |
| language | English |
| last_indexed | 2024-04-10T11:53:17Z |
| publishDate | 2018-08-01 |
| publisher | Istanbul Gelisim University Press |
| record_format | Article |
| series | İstanbul Gelişim Üniversitesi Sağlık Bilimleri Dergisi |
| spelling | doaj.art-01501b507bfd4ef3867cb3228836eec52023-02-15T16:17:00ZengIstanbul Gelisim University Pressİstanbul Gelişim Üniversitesi Sağlık Bilimleri Dergisi2536-44992602-26052018-08-015407420155Examination of Age Related Volume Changes in Brain by Magnetic Resonance Imaging MethodTuncay Varol0Ceyda Hayretdağ Örs1Necip Ozan Tiryakioğlu2MANISA CELAL BAYAR UNIVERSITYUNIVERSITY OF HEALTH SCIENCESISTANBUL GELISIM UNIVERSITYAim: Normal brain aging is accompanied by cognitive decline. Determination of age-related changes in the brain helps in understanding the healthy aging process. Our aim was to examine the volume changes occurring due to advanced age by investigating the age-related changes in brain during normal aging process. Method: This study was carried out on the magnetic resonance (MR) images of 29 healthy subjects consisting of 13 males and 16 females between the ages of 20 to 80. Volumes of right and left cerebral hemispheres, right and left frontal lobes, and right and left temporal lobes were measured by Cavalieri sections method on MR images. Findings: A significant age-related decline in the volumes of all investigated regions (p<0.05) was observed. The decline in volume is higher in males in comparison to females. Additionally, it has been observed that in male subjects, the volume of right hemisphere, right frontal lobe and right temporal lobe showed more signs of atrophy than left side; whereas in females, the volume of right frontal lobe showed a more prominent decline than its left frontal lobe. Conclusion: An age-related decline in brain volume has been detected for both sexes; however male subjects suffered a more prominent decline than females. We believe that the reason behind this more significant decline might be the effect of gonodal hormones.https://dergipark.org.tr/tr/pub/igusabder/issue/38973/401823agingbrainmriyaşlanmabeyinmrg |
| spellingShingle | Tuncay Varol Ceyda Hayretdağ Örs Necip Ozan Tiryakioğlu Examination of Age Related Volume Changes in Brain by Magnetic Resonance Imaging Method İstanbul Gelişim Üniversitesi Sağlık Bilimleri Dergisi aging brain mri yaşlanma beyin mrg |
| title | Examination of Age Related Volume Changes in Brain by Magnetic Resonance Imaging Method |
| title_full | Examination of Age Related Volume Changes in Brain by Magnetic Resonance Imaging Method |
| title_fullStr | Examination of Age Related Volume Changes in Brain by Magnetic Resonance Imaging Method |
| title_full_unstemmed | Examination of Age Related Volume Changes in Brain by Magnetic Resonance Imaging Method |
| title_short | Examination of Age Related Volume Changes in Brain by Magnetic Resonance Imaging Method |
| title_sort | examination of age related volume changes in brain by magnetic resonance imaging method |
| topic | aging brain mri yaşlanma beyin mrg |
| url | https://dergipark.org.tr/tr/pub/igusabder/issue/38973/401823 |
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