Stem cell-derived exosomal transcriptomes for wound healing
Wound healing is a complex and integrated process of the interaction of various components within the injured tissue. Accumulating evidence suggested that stem cell-derived exosomal transcriptomes could serve as key regulatory molecules in wound healing in stem cell therapy. Stem cell-derived exosom...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-08-01
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| Series: | Frontiers in Surgery |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fsurg.2022.933781/full |
| _version_ | 1798042971565719552 |
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| author | Guiling Chen Guiling Chen Guiling Chen Guiling Chen Hankun Chen Xiang Zeng Xiang Zeng Xiang Zeng Xiang Zeng Wei Zhu Wei Zhu Wei Zhu |
| author_facet | Guiling Chen Guiling Chen Guiling Chen Guiling Chen Hankun Chen Xiang Zeng Xiang Zeng Xiang Zeng Xiang Zeng Wei Zhu Wei Zhu Wei Zhu |
| author_sort | Guiling Chen |
| collection | DOAJ |
| description | Wound healing is a complex and integrated process of the interaction of various components within the injured tissue. Accumulating evidence suggested that stem cell-derived exosomal transcriptomes could serve as key regulatory molecules in wound healing in stem cell therapy. Stem cell-derived exosomal transcriptomes mainly consist of long noncoding RNAs (lncRNAs), microRNAs (miRNAs), circular RNAs (circRNAs) and messenger RNAs (mRNAs). In this article we presented a brief introduction on the wound repair process and exosomal transcriptomes. Meanwhile, we summarized our current knowledge of the involvement of exosomal transcriptomes in physiological and pathological wound repair process including inflammation, angiogenesis, and scar formation. |
| first_indexed | 2024-04-11T22:42:57Z |
| format | Article |
| id | doaj.art-0151c234015b4b1a850fd8283e55a848 |
| institution | Directory Open Access Journal |
| issn | 2296-875X |
| language | English |
| last_indexed | 2024-04-11T22:42:57Z |
| publishDate | 2022-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Surgery |
| spelling | doaj.art-0151c234015b4b1a850fd8283e55a8482022-12-22T03:58:53ZengFrontiers Media S.A.Frontiers in Surgery2296-875X2022-08-01910.3389/fsurg.2022.933781933781Stem cell-derived exosomal transcriptomes for wound healingGuiling Chen0Guiling Chen1Guiling Chen2Guiling Chen3Hankun Chen4Xiang Zeng5Xiang Zeng6Xiang Zeng7Xiang Zeng8Wei Zhu9Wei Zhu10Wei Zhu11The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, ChinaThe Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, ChinaNational Institute of Stem Cell Clinical Research, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, ChinaGuangdong Provincial Academy of Chinese Medical Sciences, Guangzhou, ChinaResearch and Development Department, Guangzhou Qinglan Biotechnology Company Limited, Guangzhou, ChinaThe Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, ChinaThe Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, ChinaNational Institute of Stem Cell Clinical Research, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, ChinaGuangdong Provincial Academy of Chinese Medical Sciences, Guangzhou, ChinaThe Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, ChinaThe Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, ChinaGuangdong Provincial Academy of Chinese Medical Sciences, Guangzhou, ChinaWound healing is a complex and integrated process of the interaction of various components within the injured tissue. Accumulating evidence suggested that stem cell-derived exosomal transcriptomes could serve as key regulatory molecules in wound healing in stem cell therapy. Stem cell-derived exosomal transcriptomes mainly consist of long noncoding RNAs (lncRNAs), microRNAs (miRNAs), circular RNAs (circRNAs) and messenger RNAs (mRNAs). In this article we presented a brief introduction on the wound repair process and exosomal transcriptomes. Meanwhile, we summarized our current knowledge of the involvement of exosomal transcriptomes in physiological and pathological wound repair process including inflammation, angiogenesis, and scar formation.https://www.frontiersin.org/articles/10.3389/fsurg.2022.933781/fullwound healingstem cellexosomemicroRNAlong noncoding RNAcircular RNA |
| spellingShingle | Guiling Chen Guiling Chen Guiling Chen Guiling Chen Hankun Chen Xiang Zeng Xiang Zeng Xiang Zeng Xiang Zeng Wei Zhu Wei Zhu Wei Zhu Stem cell-derived exosomal transcriptomes for wound healing Frontiers in Surgery wound healing stem cell exosome microRNA long noncoding RNA circular RNA |
| title | Stem cell-derived exosomal transcriptomes for wound healing |
| title_full | Stem cell-derived exosomal transcriptomes for wound healing |
| title_fullStr | Stem cell-derived exosomal transcriptomes for wound healing |
| title_full_unstemmed | Stem cell-derived exosomal transcriptomes for wound healing |
| title_short | Stem cell-derived exosomal transcriptomes for wound healing |
| title_sort | stem cell derived exosomal transcriptomes for wound healing |
| topic | wound healing stem cell exosome microRNA long noncoding RNA circular RNA |
| url | https://www.frontiersin.org/articles/10.3389/fsurg.2022.933781/full |
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