One-Stage Anterolateral Debridement, Bone Grafting, and Internal Fixation for Treating Lumbosacral Tuberculosis
Study DesignRetrospective case series.PurposeTo investigate the clinical efficacy and feasibility of one-stage anterolateral debridement, bone grafting, and internal fixation for treating lumbosacral tuberculosis.Overview of LiteratureThere has been no consensus regarding the optimal means of treati...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Korean Spine Society
2017-04-01
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| Series: | Asian Spine Journal |
| Subjects: | |
| Online Access: | http://www.asianspinejournal.org/upload/pdf/asj-11-305.pdf |
| _version_ | 1819227597586825216 |
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| author | Tao Zhang Lihua Ma Xu Lan Ping Zhen Shiyong Wang Zhilin Li |
| author_facet | Tao Zhang Lihua Ma Xu Lan Ping Zhen Shiyong Wang Zhilin Li |
| author_sort | Tao Zhang |
| collection | DOAJ |
| description | Study DesignRetrospective case series.PurposeTo investigate the clinical efficacy and feasibility of one-stage anterolateral debridement, bone grafting, and internal fixation for treating lumbosacral tuberculosis.Overview of LiteratureThere has been no consensus regarding the optimal means of treating lumbosacral tuberculosis. The one-stage anterolateral extraperitoneal approach for radical debridement, bone grafting, and internal fixation for treating lumbosacral tuberculosis is rare in literature.MethodsTwenty-one patients with lumbosacral tuberculosis were retrospectively analyzed. All patients underwent the surgery of anterolateral debridement after regularly antituberculous drugs therapy. We evaluated the erythrocyte sedimentation rate, C-reactive protein, radiography, computed tomography, magnetic resonance imaging, visual analogue score, and Oswestry disability index before and after surgery.ResultsAll patients completed a follow-up survey 9–48 months after surgery. All patients' wounds healed well without chronic infection or sinus formation, and all patients with low-back pain reported relief after surgery. All cases had no tuberculosis recurrence. Solid bony fusion was achieved within 6–12 months. At final follow-up, evaluated the erythrocyte sedimentation rate decreased from 38.1±12.5 to 11.3±7.1 mm/hr, C-reactive protein decreased from 6.2±4.2 to 1.6±1.3 mg/dL, the visual analog scale score decreased from 4.6±1.1 to 1.4±1.0, the Oswestry disability index score decreased from 50.2%±11.9% to 13.0%±6.6%, and the lumbosacral angle increased from 20.0°±4.8° to 29.0°±3.9° (p<0.05).ConclusionsOne-stage anterolateral debridement, bone grafting, and internal instrument fixation for treating lumbosacral tuberculosis is safe and effective. |
| first_indexed | 2024-12-23T10:43:55Z |
| format | Article |
| id | doaj.art-0151f5a7946748aa84269a1e38176e56 |
| institution | Directory Open Access Journal |
| issn | 1976-1902 1976-7846 |
| language | English |
| last_indexed | 2024-12-23T10:43:55Z |
| publishDate | 2017-04-01 |
| publisher | Korean Spine Society |
| record_format | Article |
| series | Asian Spine Journal |
| spelling | doaj.art-0151f5a7946748aa84269a1e38176e562022-12-21T17:50:05ZengKorean Spine SocietyAsian Spine Journal1976-19021976-78462017-04-0111230531310.4184/asj.2017.11.2.305219One-Stage Anterolateral Debridement, Bone Grafting, and Internal Fixation for Treating Lumbosacral TuberculosisTao Zhang0Lihua Ma1Xu Lan2Ping Zhen3Shiyong Wang4Zhilin Li5Department of Spine Surgery, Lanzhou General Hospital, Lanzhou Command of Chinese PLA, Lanzhou, China.Endocrinology Department, The First Hospital of Lanzhou University, Lanzhou, China.Department of Spine Surgery, Lanzhou General Hospital, Lanzhou Command of Chinese PLA, Lanzhou, China.Department of Spine Surgery, Lanzhou General Hospital, Lanzhou Command of Chinese PLA, Lanzhou, China.Department of Spine Surgery, Lanzhou General Hospital, Lanzhou Command of Chinese PLA, Lanzhou, China.Department of Spine Surgery, Lanzhou General Hospital, Lanzhou Command of Chinese PLA, Lanzhou, China.Study DesignRetrospective case series.PurposeTo investigate the clinical efficacy and feasibility of one-stage anterolateral debridement, bone grafting, and internal fixation for treating lumbosacral tuberculosis.Overview of LiteratureThere has been no consensus regarding the optimal means of treating lumbosacral tuberculosis. The one-stage anterolateral extraperitoneal approach for radical debridement, bone grafting, and internal fixation for treating lumbosacral tuberculosis is rare in literature.MethodsTwenty-one patients with lumbosacral tuberculosis were retrospectively analyzed. All patients underwent the surgery of anterolateral debridement after regularly antituberculous drugs therapy. We evaluated the erythrocyte sedimentation rate, C-reactive protein, radiography, computed tomography, magnetic resonance imaging, visual analogue score, and Oswestry disability index before and after surgery.ResultsAll patients completed a follow-up survey 9–48 months after surgery. All patients' wounds healed well without chronic infection or sinus formation, and all patients with low-back pain reported relief after surgery. All cases had no tuberculosis recurrence. Solid bony fusion was achieved within 6–12 months. At final follow-up, evaluated the erythrocyte sedimentation rate decreased from 38.1±12.5 to 11.3±7.1 mm/hr, C-reactive protein decreased from 6.2±4.2 to 1.6±1.3 mg/dL, the visual analog scale score decreased from 4.6±1.1 to 1.4±1.0, the Oswestry disability index score decreased from 50.2%±11.9% to 13.0%±6.6%, and the lumbosacral angle increased from 20.0°±4.8° to 29.0°±3.9° (p<0.05).ConclusionsOne-stage anterolateral debridement, bone grafting, and internal instrument fixation for treating lumbosacral tuberculosis is safe and effective.http://www.asianspinejournal.org/upload/pdf/asj-11-305.pdfLumbosacral tuberculosisTuberculous spondylitisAnterolateral debridementExtraperitoneal debridementInternal fixation |
| spellingShingle | Tao Zhang Lihua Ma Xu Lan Ping Zhen Shiyong Wang Zhilin Li One-Stage Anterolateral Debridement, Bone Grafting, and Internal Fixation for Treating Lumbosacral Tuberculosis Asian Spine Journal Lumbosacral tuberculosis Tuberculous spondylitis Anterolateral debridement Extraperitoneal debridement Internal fixation |
| title | One-Stage Anterolateral Debridement, Bone Grafting, and Internal Fixation for Treating Lumbosacral Tuberculosis |
| title_full | One-Stage Anterolateral Debridement, Bone Grafting, and Internal Fixation for Treating Lumbosacral Tuberculosis |
| title_fullStr | One-Stage Anterolateral Debridement, Bone Grafting, and Internal Fixation for Treating Lumbosacral Tuberculosis |
| title_full_unstemmed | One-Stage Anterolateral Debridement, Bone Grafting, and Internal Fixation for Treating Lumbosacral Tuberculosis |
| title_short | One-Stage Anterolateral Debridement, Bone Grafting, and Internal Fixation for Treating Lumbosacral Tuberculosis |
| title_sort | one stage anterolateral debridement bone grafting and internal fixation for treating lumbosacral tuberculosis |
| topic | Lumbosacral tuberculosis Tuberculous spondylitis Anterolateral debridement Extraperitoneal debridement Internal fixation |
| url | http://www.asianspinejournal.org/upload/pdf/asj-11-305.pdf |
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