Paralichthys olivaceus MLKL-mediated necroptosis is activated by RIPK1/3 and involved in anti-microbial immunity

Paralichthys olivaceus MLKL-mediated necroptosis is activated by RIPK1/3 and involved in anti-microbial immunity

Necroptosis is a type of proinflammatory programmed necrosis essential for innate immunity. The receptor interacting protein kinases 1/3 (RIPK1/3) and the substrate mixed lineage kinase domain-like protein (MLKL) are core components of the necroptotic axis. The activation and immunological function...

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Bibliographic Details
Main Authors: Kangwei Hao, Hang Xu, Shuai Jiang, Li Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Immunology
Subjects:
Paralichthys olivaceus
necroptosis
RIPK1
RIPK3
MLKL
immune defense
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1348866/full

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