Autophagy Deficiency by Atg4B Loss Leads to Metabolomic Alterations in Mice

Autophagy Deficiency by Atg4B Loss Leads to Metabolomic Alterations in Mice

Autophagy is an essential protective mechanism that allows mammalian cells to cope with a variety of stressors and contributes to maintaining cellular and tissue homeostasis. Due to these crucial roles and also to the fact that autophagy malfunction has been described in a wide range of pathologies,...

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Bibliographic Details
Main Authors: Gemma G. Martínez-García, Raúl F. Pérez, Álvaro F. Fernández, Sylvere Durand, Guido Kroemer, Guillermo Mariño
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Metabolites
Subjects:
autophagy
metabolome
ATG4
aging
autophagosome
ATG8
Online Access:https://www.mdpi.com/2218-1989/11/8/481

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