Opstacles in neuropathic pain treatment in the developing country: Neuropathic pain treatment

Introduction: Neuropathic pain is initiated or caused by a primary lesion or dysfunction in the peripheral or central nervous system. The central neuropathic pain includes thalamic pain syndrome, pain related to multiple sclerosis, poststroke pain, post spinal cord injury pain. Almost 60% of patient...

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Main Authors: Jovičić Jelena, Volaš Ljubiša, Brkić Tatjana, Terzić Branka, Garić Aleksandra, Gvozdić Branka, Antonijević Vesna
Format: Article
Language:English
Published: Serbian Society of Anesthesiologists and Intensivists 2018-01-01
Series:Serbian Journal of Anesthesia and Intensive Therapy
Subjects:
Online Access:https://scindeks-clanci.ceon.rs/data/pdf/2217-7744/2018/2217-77441804103J.pdf
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author Jovičić Jelena
Volaš Ljubiša
Brkić Tatjana
Terzić Branka
Garić Aleksandra
Gvozdić Branka
Antonijević Vesna
author_facet Jovičić Jelena
Volaš Ljubiša
Brkić Tatjana
Terzić Branka
Garić Aleksandra
Gvozdić Branka
Antonijević Vesna
author_sort Jovičić Jelena
collection DOAJ
description Introduction: Neuropathic pain is initiated or caused by a primary lesion or dysfunction in the peripheral or central nervous system. The central neuropathic pain includes thalamic pain syndrome, pain related to multiple sclerosis, poststroke pain, post spinal cord injury pain. Almost 60% of patients with spinal cord injuries have neuropathic pain whose treatment requires great socioeconomic support for a long time. Case Report: Male, 56 years old, previously healthy, was examined at the Outpatient pain Clinic, Clinical Centre of Serbia. He complained about a strong pain in both legs and a sense of tightening around the trunk. The pain was present on rest and getting worse on mobilization, intensity 7-10/10 by NRS. In 2008. after falling into the shallow water, he sustained comminuted C7 fracture resulting in quadriplegia. He was operated and regained motor skills in both arms with some residual sensory deficits. Detailed neurological examination diagnosed the presence of neuropathic pain in the trunk (T4-L1 dermatome being the worst pain with hyperalgesia, dysesthesia, hyperpathia), with sensitivity fairly preserved. Regarding therapy, only fentanyl patches helped with the dose increase but tightening sense persisted. Combined lidocaine and ketamine infusion was applied - the response was temporarily good. The patient still feels pain and uses fentanyl patches, baclofen and physical therapy. Discussion: Treatment of neuropathic pain represents a great socioeconomic problem even for developed countries because there is no benefit of conventional pharmacologic therapy in long-term use. Also, neuromodulatory therapy methods provide the most benefits for this group of patients but demand trained personnel and use of expensive equipment. Conclusion: This case is a good example of difficulties regarding treatment of this type of chronic pain in a developing country: limits of pharmacotherapy, no trained doctors for implantation of neuromodulatory devices, high price of neuromodulatory devices.
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spelling doaj.art-0157fffc13194c2f847c4b98542d0f1d2022-12-21T18:50:51ZengSerbian Society of Anesthesiologists and IntensivistsSerbian Journal of Anesthesia and Intensive Therapy2217-77442466-488X2018-01-01403-41031072217-77441804103JOpstacles in neuropathic pain treatment in the developing country: Neuropathic pain treatmentJovičić Jelena0Volaš Ljubiša1Brkić Tatjana2Terzić Branka3Garić Aleksandra4Gvozdić Branka5Antonijević Vesna6Klinički centar Srbije, Centar za anesteziologiju i reanimatologiju, BeogradKlinički centar Srbije, Centar za anesteziologiju i reanimatologiju, BeogradKlinički centar Srbije, Centar za anesteziologiju i reanimatologiju, BeogradKlinički centar Srbije, Centar za anesteziologiju i reanimatologiju, BeogradKlinički centar Srbije, Centar za anesteziologiju i reanimatologiju, BeogradKlinički centar Srbije, Centar za anesteziologiju i reanimatologiju, BeogradKlinički centar Srbije, Centar za anesteziologiju i reanimatologiju, BeogradIntroduction: Neuropathic pain is initiated or caused by a primary lesion or dysfunction in the peripheral or central nervous system. The central neuropathic pain includes thalamic pain syndrome, pain related to multiple sclerosis, poststroke pain, post spinal cord injury pain. Almost 60% of patients with spinal cord injuries have neuropathic pain whose treatment requires great socioeconomic support for a long time. Case Report: Male, 56 years old, previously healthy, was examined at the Outpatient pain Clinic, Clinical Centre of Serbia. He complained about a strong pain in both legs and a sense of tightening around the trunk. The pain was present on rest and getting worse on mobilization, intensity 7-10/10 by NRS. In 2008. after falling into the shallow water, he sustained comminuted C7 fracture resulting in quadriplegia. He was operated and regained motor skills in both arms with some residual sensory deficits. Detailed neurological examination diagnosed the presence of neuropathic pain in the trunk (T4-L1 dermatome being the worst pain with hyperalgesia, dysesthesia, hyperpathia), with sensitivity fairly preserved. Regarding therapy, only fentanyl patches helped with the dose increase but tightening sense persisted. Combined lidocaine and ketamine infusion was applied - the response was temporarily good. The patient still feels pain and uses fentanyl patches, baclofen and physical therapy. Discussion: Treatment of neuropathic pain represents a great socioeconomic problem even for developed countries because there is no benefit of conventional pharmacologic therapy in long-term use. Also, neuromodulatory therapy methods provide the most benefits for this group of patients but demand trained personnel and use of expensive equipment. Conclusion: This case is a good example of difficulties regarding treatment of this type of chronic pain in a developing country: limits of pharmacotherapy, no trained doctors for implantation of neuromodulatory devices, high price of neuromodulatory devices.https://scindeks-clanci.ceon.rs/data/pdf/2217-7744/2018/2217-77441804103J.pdfneuropathic painquadriplegiadermatomesensory deficit
spellingShingle Jovičić Jelena
Volaš Ljubiša
Brkić Tatjana
Terzić Branka
Garić Aleksandra
Gvozdić Branka
Antonijević Vesna
Opstacles in neuropathic pain treatment in the developing country: Neuropathic pain treatment
Serbian Journal of Anesthesia and Intensive Therapy
neuropathic pain
quadriplegia
dermatome
sensory deficit
title Opstacles in neuropathic pain treatment in the developing country: Neuropathic pain treatment
title_full Opstacles in neuropathic pain treatment in the developing country: Neuropathic pain treatment
title_fullStr Opstacles in neuropathic pain treatment in the developing country: Neuropathic pain treatment
title_full_unstemmed Opstacles in neuropathic pain treatment in the developing country: Neuropathic pain treatment
title_short Opstacles in neuropathic pain treatment in the developing country: Neuropathic pain treatment
title_sort opstacles in neuropathic pain treatment in the developing country neuropathic pain treatment
topic neuropathic pain
quadriplegia
dermatome
sensory deficit
url https://scindeks-clanci.ceon.rs/data/pdf/2217-7744/2018/2217-77441804103J.pdf
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