Exosomes from glioma cells induce a tumor-like phenotype in mesenchymal stem cells by activating glycolysis

Exosomes from glioma cells induce a tumor-like phenotype in mesenchymal stem cells by activating glycolysis

Abstract Background Exosomes are nanoscale membrane vesicles secreted by both normal and cancer cells, and cancer cell-derived exosomes play an important role in the cross-talk between cancer cells and other cellular components in the tumor microenvironment. Mesenchymal stem cells (MSCs) have tropis...

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Bibliographic Details
Main Authors: Zhanjun Ma, Xue Cui, Li Lu, Guohu Chen, Yang Yang, Yan Hu, Yubao Lu, Zhangqi Cao, Yan Wang, Xuexi Wang
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Stem Cell Research & Therapy
Subjects:
Exosomes
Glioma cells
Glycolytic pathway
Tumor-like phenotype transformation
Mesenchymal stem cells
Proteomics
Online Access:http://link.springer.com/article/10.1186/s13287-019-1149-5

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