Looking for Possible Benefits of Combining Short-Chain Fructo-Oligosaccharides (scFOS) with <i>Saccharomyces cerevisiae</i> Sc 47 on Weaned Pigs Orally Challenged with <i>Escherichia coli</i> F4<sup>+</sup>
The objective of this work was to evaluate the effect of supplementing short-chain fructo-oligosaccharides (scFOS) combined or not with live yeast <i>Saccharomyces cerevisiae</i> Sc 47 on weanling pigs challenged with <i>Escherichia coli</i> F4<sup>+</sup>. We all...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-02-01
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| Series: | Animals |
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| Online Access: | https://www.mdpi.com/2076-2615/13/3/526 |
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| author | Laia Ferreres-Serafini Lorena Castillejos Marga Martín Cindy Le Bourgot Susana M. Martín-Orúe |
| author_facet | Laia Ferreres-Serafini Lorena Castillejos Marga Martín Cindy Le Bourgot Susana M. Martín-Orúe |
| author_sort | Laia Ferreres-Serafini |
| collection | DOAJ |
| description | The objective of this work was to evaluate the effect of supplementing short-chain fructo-oligosaccharides (scFOS) combined or not with live yeast <i>Saccharomyces cerevisiae</i> Sc 47 on weanling pigs challenged with <i>Escherichia coli</i> F4<sup>+</sup>. We allocated ninety-six piglets to four experimental diets: control (CTR); supplemented with scFOS (5 g/kg Profeed<sup>®</sup> P95) (scFOS); <i>S. cerevisiae</i> Sc 47 (1 g/kg Actisaf<sup>®</sup> Sc 47 HR +) (YEA); or both (SYN). Parameters included: performance; <i>E. coli</i> F4<sup>+</sup> detection; fermentation activity; inflammatory biomarkers; and ileal histomorphology. Our results showed that supplementing scFOS was able to reduce the incidence of diarrhea, and both supplements were able to lower counts of EHEC along the gut. Supplementing scFOS was mostly associated with changes in the gut ecosystem and increases in the lactobacilli population, while <i>S. cerevisiae</i> Sc 47 registered increases in the numbers of ileal intraepithelial lymphocytes. The synbiotic mixture showed the lowest diarrhea incidence and fecal scores, benefiting from complementary modes of action and possible synergistic effects due to a hypothesized yeast–LAB cross-feeding phenomenon in the foregut. In conclusion, our results evidence that supplementing scFOS or <i>Saccharomyces cerevisiae</i> Sc 47 is efficacious to fight post-weaning colibacillosis, and combining both could be beneficial in high-risk scenarios. |
| first_indexed | 2024-03-11T09:53:36Z |
| format | Article |
| id | doaj.art-015de42ba2d1439685bab17657c30e1a |
| institution | Directory Open Access Journal |
| issn | 2076-2615 |
| language | English |
| last_indexed | 2024-03-11T09:53:36Z |
| publishDate | 2023-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Animals |
| spelling | doaj.art-015de42ba2d1439685bab17657c30e1a2023-11-16T16:02:06ZengMDPI AGAnimals2076-26152023-02-0113352610.3390/ani13030526Looking for Possible Benefits of Combining Short-Chain Fructo-Oligosaccharides (scFOS) with <i>Saccharomyces cerevisiae</i> Sc 47 on Weaned Pigs Orally Challenged with <i>Escherichia coli</i> F4<sup>+</sup>Laia Ferreres-Serafini0Lorena Castillejos1Marga Martín2Cindy Le Bourgot3Susana M. Martín-Orúe4Animal Nutrition and Welfare Service (SNIBA), Universitat Autònoma de Barcelona (UAB), 08193 Bellaterra, SpainAnimal Nutrition and Welfare Service (SNIBA), Universitat Autònoma de Barcelona (UAB), 08193 Bellaterra, SpainDepartament de Sanitat i Anatomia Animals, Universitat Autònoma de Barcelona (UAB), 08193 Bellaterra, SpainTereos, R&D, 67390 Moussy-le-Vieux, FranceAnimal Nutrition and Welfare Service (SNIBA), Universitat Autònoma de Barcelona (UAB), 08193 Bellaterra, SpainThe objective of this work was to evaluate the effect of supplementing short-chain fructo-oligosaccharides (scFOS) combined or not with live yeast <i>Saccharomyces cerevisiae</i> Sc 47 on weanling pigs challenged with <i>Escherichia coli</i> F4<sup>+</sup>. We allocated ninety-six piglets to four experimental diets: control (CTR); supplemented with scFOS (5 g/kg Profeed<sup>®</sup> P95) (scFOS); <i>S. cerevisiae</i> Sc 47 (1 g/kg Actisaf<sup>®</sup> Sc 47 HR +) (YEA); or both (SYN). Parameters included: performance; <i>E. coli</i> F4<sup>+</sup> detection; fermentation activity; inflammatory biomarkers; and ileal histomorphology. Our results showed that supplementing scFOS was able to reduce the incidence of diarrhea, and both supplements were able to lower counts of EHEC along the gut. Supplementing scFOS was mostly associated with changes in the gut ecosystem and increases in the lactobacilli population, while <i>S. cerevisiae</i> Sc 47 registered increases in the numbers of ileal intraepithelial lymphocytes. The synbiotic mixture showed the lowest diarrhea incidence and fecal scores, benefiting from complementary modes of action and possible synergistic effects due to a hypothesized yeast–LAB cross-feeding phenomenon in the foregut. In conclusion, our results evidence that supplementing scFOS or <i>Saccharomyces cerevisiae</i> Sc 47 is efficacious to fight post-weaning colibacillosis, and combining both could be beneficial in high-risk scenarios.https://www.mdpi.com/2076-2615/13/3/526weaning piglet<i>Escherichia coli</i> F4<sup>+</sup>probioticprebioticsynbioticfructo-oligosaccharides |
| spellingShingle | Laia Ferreres-Serafini Lorena Castillejos Marga Martín Cindy Le Bourgot Susana M. Martín-Orúe Looking for Possible Benefits of Combining Short-Chain Fructo-Oligosaccharides (scFOS) with <i>Saccharomyces cerevisiae</i> Sc 47 on Weaned Pigs Orally Challenged with <i>Escherichia coli</i> F4<sup>+</sup> Animals weaning piglet <i>Escherichia coli</i> F4<sup>+</sup> probiotic prebiotic synbiotic fructo-oligosaccharides |
| title | Looking for Possible Benefits of Combining Short-Chain Fructo-Oligosaccharides (scFOS) with <i>Saccharomyces cerevisiae</i> Sc 47 on Weaned Pigs Orally Challenged with <i>Escherichia coli</i> F4<sup>+</sup> |
| title_full | Looking for Possible Benefits of Combining Short-Chain Fructo-Oligosaccharides (scFOS) with <i>Saccharomyces cerevisiae</i> Sc 47 on Weaned Pigs Orally Challenged with <i>Escherichia coli</i> F4<sup>+</sup> |
| title_fullStr | Looking for Possible Benefits of Combining Short-Chain Fructo-Oligosaccharides (scFOS) with <i>Saccharomyces cerevisiae</i> Sc 47 on Weaned Pigs Orally Challenged with <i>Escherichia coli</i> F4<sup>+</sup> |
| title_full_unstemmed | Looking for Possible Benefits of Combining Short-Chain Fructo-Oligosaccharides (scFOS) with <i>Saccharomyces cerevisiae</i> Sc 47 on Weaned Pigs Orally Challenged with <i>Escherichia coli</i> F4<sup>+</sup> |
| title_short | Looking for Possible Benefits of Combining Short-Chain Fructo-Oligosaccharides (scFOS) with <i>Saccharomyces cerevisiae</i> Sc 47 on Weaned Pigs Orally Challenged with <i>Escherichia coli</i> F4<sup>+</sup> |
| title_sort | looking for possible benefits of combining short chain fructo oligosaccharides scfos with i saccharomyces cerevisiae i sc 47 on weaned pigs orally challenged with i escherichia coli i f4 sup sup |
| topic | weaning piglet <i>Escherichia coli</i> F4<sup>+</sup> probiotic prebiotic synbiotic fructo-oligosaccharides |
| url | https://www.mdpi.com/2076-2615/13/3/526 |
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