<i>RAD52</i> Functions in Homologous Recombination and Its Importance on Genomic Integrity Maintenance and Cancer Therapy

Genomes are continually subjected to DNA damage whether they are induced from intrinsic physiological processes or extrinsic agents. Double-stranded breaks (DSBs) are the most injurious type of DNA damage, being induced by ionizing radiation (IR) and cytotoxic agents used in cancer treatment. The fa...

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Bibliographic Details
Main Authors: Augusto Nogueira, Mara Fernandes, Raquel Catarino, Rui Medeiros
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/11/11/1622