Dengue fever as a potential cause of sickle cell intrahepatic cholestasis: A report of two cases
Abstract Sickle cell intrahepatic cholestasis is a potentially fatal syndrome characterized by jaundice, painful hepatomegaly, and organ dysfunction. Two cases of sickle cell intrahepatic cholestasis associated with dengue fever were described. Endothelial damage/dysfunction is a mechanism involved...
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Medicina Tropical (SBMT)
2021-07-01
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| Series: | Revista da Sociedade Brasileira de Medicina Tropical |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822021000100724&tlng=en |
| _version_ | 1811245398742794240 |
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| author | Leonardo Rodrigues de Oliveira Ana Laura Castro Costa Paula Veloso Almeida Luzia Beatriz Ribeiro Zago Vanessa Afonso da Silva Sheila Soares-Silva |
| author_facet | Leonardo Rodrigues de Oliveira Ana Laura Castro Costa Paula Veloso Almeida Luzia Beatriz Ribeiro Zago Vanessa Afonso da Silva Sheila Soares-Silva |
| author_sort | Leonardo Rodrigues de Oliveira |
| collection | DOAJ |
| description | Abstract Sickle cell intrahepatic cholestasis is a potentially fatal syndrome characterized by jaundice, painful hepatomegaly, and organ dysfunction. Two cases of sickle cell intrahepatic cholestasis associated with dengue fever were described. Endothelial damage/dysfunction is a mechanism involved in severe hepatobiliary complications related to sickle cell diseases. However, the reasons for the lack of increase in the admission of patients with sickle cell disease having severe acute hepatobiliary complications triggered by endothelial damage/dysfunction due to dengue fever remain unknown. This study describes the first association between sickle cell intrahepatic cholestasis and dengue fever. |
| first_indexed | 2024-04-12T14:39:26Z |
| format | Article |
| id | doaj.art-016297ac5a3d48b585da669600e44055 |
| institution | Directory Open Access Journal |
| issn | 1678-9849 |
| language | English |
| last_indexed | 2024-04-12T14:39:26Z |
| publishDate | 2021-07-01 |
| publisher | Sociedade Brasileira de Medicina Tropical (SBMT) |
| record_format | Article |
| series | Revista da Sociedade Brasileira de Medicina Tropical |
| spelling | doaj.art-016297ac5a3d48b585da669600e440552022-12-22T03:28:54ZengSociedade Brasileira de Medicina Tropical (SBMT)Revista da Sociedade Brasileira de Medicina Tropical1678-98492021-07-015410.1590/0037-8682-0010-2021Dengue fever as a potential cause of sickle cell intrahepatic cholestasis: A report of two casesLeonardo Rodrigues de Oliveirahttps://orcid.org/0000-0003-1882-1694Ana Laura Castro Costahttps://orcid.org/0000-0003-0344-2632Paula Veloso Almeidahttps://orcid.org/0000-0002-9973-2601Luzia Beatriz Ribeiro Zagohttps://orcid.org/0000-0001-5184-3380Vanessa Afonso da Silvahttps://orcid.org/0000-0003-0285-1178Sheila Soares-Silvahttps://orcid.org/0000-0002-9474-1381Abstract Sickle cell intrahepatic cholestasis is a potentially fatal syndrome characterized by jaundice, painful hepatomegaly, and organ dysfunction. Two cases of sickle cell intrahepatic cholestasis associated with dengue fever were described. Endothelial damage/dysfunction is a mechanism involved in severe hepatobiliary complications related to sickle cell diseases. However, the reasons for the lack of increase in the admission of patients with sickle cell disease having severe acute hepatobiliary complications triggered by endothelial damage/dysfunction due to dengue fever remain unknown. This study describes the first association between sickle cell intrahepatic cholestasis and dengue fever.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822021000100724&tlng=enDengueSickle cell diseaseEndothelial cells |
| spellingShingle | Leonardo Rodrigues de Oliveira Ana Laura Castro Costa Paula Veloso Almeida Luzia Beatriz Ribeiro Zago Vanessa Afonso da Silva Sheila Soares-Silva Dengue fever as a potential cause of sickle cell intrahepatic cholestasis: A report of two cases Revista da Sociedade Brasileira de Medicina Tropical Dengue Sickle cell disease Endothelial cells |
| title | Dengue fever as a potential cause of sickle cell intrahepatic cholestasis: A report of two cases |
| title_full | Dengue fever as a potential cause of sickle cell intrahepatic cholestasis: A report of two cases |
| title_fullStr | Dengue fever as a potential cause of sickle cell intrahepatic cholestasis: A report of two cases |
| title_full_unstemmed | Dengue fever as a potential cause of sickle cell intrahepatic cholestasis: A report of two cases |
| title_short | Dengue fever as a potential cause of sickle cell intrahepatic cholestasis: A report of two cases |
| title_sort | dengue fever as a potential cause of sickle cell intrahepatic cholestasis a report of two cases |
| topic | Dengue Sickle cell disease Endothelial cells |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822021000100724&tlng=en |
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