Understanding suicidal transitions in Australian adults: protocol for the LifeTrack prospective longitudinal cohort study

Abstract Background The factors that influence transition from suicidal ideation to a suicide attempt or remission of suicidal thoughts are poorly understood. Despite an abundance of research on risk factors for suicidal ideation, no large-scale longitudinal population-based studies have specificall...

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Main Authors: Philip J Batterham, Monica Gendi, Helen Christensen, Alison L. Calear, Fiona Shand, Matthew Sunderland, Rohan Borschmann, Michelle Banfield, Bridianne O’Dea, Mark Larsen, Cassandra Heffernan, Dominique Kazan, Aliza Werner-Seidler, Andrew J Mackinnon, Emily Hielscher, Jin Han, Katherine M Boydell, Liana Leach, Louise M Farrer
Format: Article
Language:English
Published: BMC 2023-11-01
Series:BMC Psychiatry
Subjects:
Online Access:https://doi.org/10.1186/s12888-023-05335-1
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author Philip J Batterham
Monica Gendi
Helen Christensen
Alison L. Calear
Fiona Shand
Matthew Sunderland
Rohan Borschmann
Michelle Banfield
Bridianne O’Dea
Mark Larsen
Cassandra Heffernan
Dominique Kazan
Aliza Werner-Seidler
Andrew J Mackinnon
Emily Hielscher
Jin Han
Katherine M Boydell
Liana Leach
Louise M Farrer
author_facet Philip J Batterham
Monica Gendi
Helen Christensen
Alison L. Calear
Fiona Shand
Matthew Sunderland
Rohan Borschmann
Michelle Banfield
Bridianne O’Dea
Mark Larsen
Cassandra Heffernan
Dominique Kazan
Aliza Werner-Seidler
Andrew J Mackinnon
Emily Hielscher
Jin Han
Katherine M Boydell
Liana Leach
Louise M Farrer
author_sort Philip J Batterham
collection DOAJ
description Abstract Background The factors that influence transition from suicidal ideation to a suicide attempt or remission of suicidal thoughts are poorly understood. Despite an abundance of research on risk factors for suicidal ideation, no large-scale longitudinal population-based studies have specifically recruited people with suicidal ideation to examine the mechanisms underlying critical transitions to either suicide attempt or recovery from suicidal ideation. Without longitudinal data on the psychological, behavioural, and social determinants of suicide attempt and the remission of suicidal ideation, we are unlikely to see major gains in the prevention of suicide. Aim The LifeTrack Project is a population-based longitudinal cohort study that aims to identify key modifiable risk and protective factors that predict the transition from suicidal ideation to suicide attempt or remission of suicidal ideation. We will assess theory-informed risk and protective factors using validated and efficient measures to identify distinct trajectories reflecting changes in severity of suicidal ideation and transition to suicide attempt over three years. Methods A three-year prospective population-based longitudinal cohort study will be conducted with adults from the general Australian population who initially report suicidal ideation (n = 842). Eligibility criteria include recent suicidal ideation (past 30 days), aged 18 years or older, living in Australia and fluent in English. Those with a suicide attempt in past 30 days or who are unable to participate in a long-term study will be excluded. Participants will be asked to complete online assessments related to psychopathology, cognition, psychological factors, social factors, mental health treatment use, and environmental exposures at baseline and every six months during this three-year period. One week of daily measurement bursts (ecological momentary assessments) at yearly intervals will also capture short-term fluctuations in suicidal ideation, perceived burdensomeness, thwarted belongingness, capability for suicide, and distress. Conclusion This study is intended to identify potential targets for novel and tailored therapies for people experiencing suicidal ideation and improve targeting of suicide prevention programs. Even modest improvements in current treatments may lead to important reductions in suicide attempts and deaths. Study Registration Australian New Zealand Clinical Trials Registry identifier: ACTRN12623000433606.
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spelling doaj.art-01642d4d4b684803949a64dd1f5227aa2023-11-12T12:26:04ZengBMCBMC Psychiatry1471-244X2023-11-0123111110.1186/s12888-023-05335-1Understanding suicidal transitions in Australian adults: protocol for the LifeTrack prospective longitudinal cohort studyPhilip J Batterham0Monica Gendi1Helen Christensen2Alison L. Calear3Fiona Shand4Matthew Sunderland5Rohan Borschmann6Michelle Banfield7Bridianne O’Dea8Mark Larsen9Cassandra Heffernan10Dominique Kazan11Aliza Werner-Seidler12Andrew J Mackinnon13Emily Hielscher14Jin Han15Katherine M Boydell16Liana Leach17Louise M Farrer18Centre for Mental Health Research, The Australian National UniversityCentre for Mental Health Research, The Australian National UniversityBlack Dog Institute, University of New South WalesCentre for Mental Health Research, The Australian National UniversityBlack Dog Institute, University of New South WalesThe Matilda Centre for Research in Mental health and Substance use, University of SydneyMelbourne School of Population and Global Health, Centre for Mental Health, The University of MelbourneCentre for Mental Health Research, The Australian National UniversityBlack Dog Institute, University of New South WalesBlack Dog Institute, University of New South WalesCentre for Mental Health Research, The Australian National UniversityCentre for Mental Health Research, The Australian National UniversityBlack Dog Institute, University of New South WalesBlack Dog Institute, University of New South WalesThe Council of the Queensland Institute of Medical ResearchCenter for Global Health Equity, New York University ShanghaiMelbourne School of Population and Global Health, Centre for Mental Health, The University of MelbourneNational Centre for Epidemiology and Population Health, The Australian National UniversityCentre for Mental Health Research, The Australian National UniversityAbstract Background The factors that influence transition from suicidal ideation to a suicide attempt or remission of suicidal thoughts are poorly understood. Despite an abundance of research on risk factors for suicidal ideation, no large-scale longitudinal population-based studies have specifically recruited people with suicidal ideation to examine the mechanisms underlying critical transitions to either suicide attempt or recovery from suicidal ideation. Without longitudinal data on the psychological, behavioural, and social determinants of suicide attempt and the remission of suicidal ideation, we are unlikely to see major gains in the prevention of suicide. Aim The LifeTrack Project is a population-based longitudinal cohort study that aims to identify key modifiable risk and protective factors that predict the transition from suicidal ideation to suicide attempt or remission of suicidal ideation. We will assess theory-informed risk and protective factors using validated and efficient measures to identify distinct trajectories reflecting changes in severity of suicidal ideation and transition to suicide attempt over three years. Methods A three-year prospective population-based longitudinal cohort study will be conducted with adults from the general Australian population who initially report suicidal ideation (n = 842). Eligibility criteria include recent suicidal ideation (past 30 days), aged 18 years or older, living in Australia and fluent in English. Those with a suicide attempt in past 30 days or who are unable to participate in a long-term study will be excluded. Participants will be asked to complete online assessments related to psychopathology, cognition, psychological factors, social factors, mental health treatment use, and environmental exposures at baseline and every six months during this three-year period. One week of daily measurement bursts (ecological momentary assessments) at yearly intervals will also capture short-term fluctuations in suicidal ideation, perceived burdensomeness, thwarted belongingness, capability for suicide, and distress. Conclusion This study is intended to identify potential targets for novel and tailored therapies for people experiencing suicidal ideation and improve targeting of suicide prevention programs. Even modest improvements in current treatments may lead to important reductions in suicide attempts and deaths. Study Registration Australian New Zealand Clinical Trials Registry identifier: ACTRN12623000433606.https://doi.org/10.1186/s12888-023-05335-1SuicideAttemptIdeationTransitionAustraliaCohort study
spellingShingle Philip J Batterham
Monica Gendi
Helen Christensen
Alison L. Calear
Fiona Shand
Matthew Sunderland
Rohan Borschmann
Michelle Banfield
Bridianne O’Dea
Mark Larsen
Cassandra Heffernan
Dominique Kazan
Aliza Werner-Seidler
Andrew J Mackinnon
Emily Hielscher
Jin Han
Katherine M Boydell
Liana Leach
Louise M Farrer
Understanding suicidal transitions in Australian adults: protocol for the LifeTrack prospective longitudinal cohort study
BMC Psychiatry
Suicide
Attempt
Ideation
Transition
Australia
Cohort study
title Understanding suicidal transitions in Australian adults: protocol for the LifeTrack prospective longitudinal cohort study
title_full Understanding suicidal transitions in Australian adults: protocol for the LifeTrack prospective longitudinal cohort study
title_fullStr Understanding suicidal transitions in Australian adults: protocol for the LifeTrack prospective longitudinal cohort study
title_full_unstemmed Understanding suicidal transitions in Australian adults: protocol for the LifeTrack prospective longitudinal cohort study
title_short Understanding suicidal transitions in Australian adults: protocol for the LifeTrack prospective longitudinal cohort study
title_sort understanding suicidal transitions in australian adults protocol for the lifetrack prospective longitudinal cohort study
topic Suicide
Attempt
Ideation
Transition
Australia
Cohort study
url https://doi.org/10.1186/s12888-023-05335-1
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