GPX3-Mediated Oxidative Stress Affects Pyrimidine Metabolism Levels in Stomach Adenocarcinoma via the AMPK/mTOR Pathway

GPX3-Mediated Oxidative Stress Affects Pyrimidine Metabolism Levels in Stomach Adenocarcinoma via the AMPK/mTOR Pathway

Background. Amino acid metabolism, including ATP production, nucleotide synthesis, and redox homeostatic processes, are associated with proliferation and differentiation of tumor cells. This study aimed to identify novel prognostic biomarkers and potential therapeutic targets of amino acid metabolis...

Full description

Bibliographic Details
Main Authors:	Yaowen Zhang, Yixin Yang, Shanshan Kuang, Yang Zhang, Hancheng Qin, Jisheng Xie
Format:	Article
Language:	English
Published:	Wiley 2024-01-01
Series:	International Journal of Clinical Practice
Online Access:	http://dx.doi.org/10.1155/2024/6875417

Similar Items

Translational regulation of GPx-1 and GPx-4 by the mTOR pathway.
by: Emily N Reinke, et al.
Published: (2014-01-01)

Active ingredients Isorhamnetin of Croci Srigma inhibit stomach adenocarcinomas progression by MAPK/mTOR signaling pathway
by: Xue-feng Shi, et al.
Published: (2023-08-01)

Wulingsan Alleviates MAFLD by Activating Autophagy via Regulating the AMPK/mTOR/ULK1 Signaling Pathway
by: Yaning Biao, et al.
Published: (2024-01-01)

Advances in Chinese medicine-mediated AMPK/mTOR signaling pathway for the treatment of osteoporosis
by: Zhang Wenhao, Yi Lin, Xiang Wenyuan, Remira·Aimaiti, Deng Yingjie, Liao Jun, Liang Zhiquan, Li Leijiang, Fang Rui
Published: (2023-10-01)

Duck Tembusu virus induces incomplete autophagy via the ERK/mTOR and AMPK/mTOR signalling pathways to promote viral replication in neuronal cells
by: Qing Wang, et al.
Published: (2023-11-01)

Panduratin A induces protective autophagy in melanoma via the AMPK and mTOR pathway
by: Lai, Siew Li, et al.
Published: (2018)

AMPK-mTOR pathway modulates glycolysis reprogramming in unexplained recurrent spontaneous abortion
by: Yihong Chen, et al.
Published: (2024-12-01)

Cytotoxicity and Autophagy Induced by Ivermectin via AMPK/mTOR Signaling Pathway in RAW264.7 Cells
by: Xiang Wang, et al.
Published: (2023-02-01)

Zearalenone Promotes Uterine Hypertrophy through AMPK/mTOR Mediated Autophagy
by: Lijie Yang, et al.
Published: (2024-02-01)

Interactions of glucose supply, AMPK and the mTOR pathway during early in vitro human neurogenesis
by: Baig, S
Published: (2023)

Mir-615-3p promotes osteosarcoma progression via the SESN2/AMPK/mTOR pathway
by: Xuecheng Yu, et al.
Published: (2024-12-01)

The Translational Regulation in mTOR Pathway
by: Miaomiao Yang, et al.
Published: (2022-06-01)

DENV-2 NS1 promotes AMPK-LKB1 interaction to activate AMPK/ERK/mTOR signaling pathway to induce autophagy
by: Ning Wu, et al.
Published: (2023-10-01)

The mTOR pathway in the antiphospholipid syndrome
by: Ji Lanlan, et al.
Published: (2023-12-01)

Protective effect of omega-3 polyunsaturated fatty acids on sepsis via the AMPK/mTOR pathway
by: Peng Liu, et al.
Published: (2023-12-01)

Bronchial thermoplasty decreases airway remodeling by inhibiting autophagy via the AMPK/mTOR signaling pathway
by: Wang Tao, et al.
Published: (2024-04-01)

Sangyod rice extract inhibits adipocyte growth and differentiation via mTOR, Akt, and AMPK pathways
by: Wanwipha Woonnoi, et al.
Published: (2023-12-01)

The AMPK–mTOR Pathway Is Inhibited by Chaihu Shugan Powder, Which Relieves Nonalcoholic Steatohepatitis by Suppressing Autophagic Ferroptosis
by: Zheng Liang, et al.
Published: (2024-01-01)

Synergistic induction of autophagy in gastric cancer by targeting CDK4/6 and MEK through AMPK/mTOR pathway
by: Hong Zhou, et al.
Published: (2024-05-01)

Osteocalcin activates lipophagy via the ADPN-AMPK/PPARα-mTOR signaling pathway in chicken embryonic hepatocyte
by: W.J. Tu, et al.
Published: (2024-02-01)

Mometasone furoate inhibits tumor progression and promotes apoptosis through activation of the AMPK/mTOR signaling pathway in osteosarcoma
by: Zhaohui Li, et al.
Published: (2024-08-01)

Ammidin ameliorates myocardial hypoxia/reoxygenation injury by inhibiting the ACSL4/AMPK/mTOR-mediated ferroptosis pathway
by: Yue Han, et al.
Published: (2023-12-01)

Resistin alleviates lipopolysaccharide-induced inflammation in bovine alveolar macrophages by activating the AMPK/mTOR signaling pathway and autophagy
by: Xiaoping Ma, et al.
Published: (2024-10-01)

O304 alleviates abdominal aortic aneurysm formation via AMPK/mTOR/MMP pathway activation
by: Daohan Sun, et al.
Published: (2024-11-01)

Neuroprotective Effect of Melatonin in a Neonatal Hypoxia–Ischemia Rat Model Is Regulated by the AMPK/mTOR Pathway
by: Efe Nacarkucuk, et al.
Published: (2024-10-01)

Ginsenoside Rg1 inhibits multiple myeloma and overcomes bortezomib resistance through AMPK-mTOR pathway
by: Li Lin, et al.
Published: (2024-07-01)

Quercetin induces autophagy-associated death in HL-60 cells through CaMKKβ/AMPK/mTOR signal pathway
by: Xiao Jie, et al.
Published: (2022-09-01)

The effects and mechanisms of isoliquiritigenin loaded nanoliposomes regulated AMPK/mTOR mediated glycolysis in colorectal cancer
by: Gang Wang, et al.
Published: (2020-01-01)

Fucoidan alleviated autoimmune diabetes in NOD mice by regulating pancreatic autophagy through the AMPK/mTOR1/TFEB pathway
by: Haiqi Gao, et al.
Published: (2024-01-01)

Enterogenic Stenotrophomonas maltophilia migrates to the mammary gland to induce mastitis by activating the calcium-ROS-AMPK-mTOR-autophagy pathway
by: Zhaoqi He, et al.
Published: (2023-12-01)

Dexmedetomidine Alleviates Ischemia/Reperfusion-Associated Acute Kidney Injury by Enhancing Autophagic Activity via the α2-AR/AMPK/mTOR Pathway
by: Bi-Ying Zhou, et al.
Published: (2023-12-01)

Glutathione Peroxidase 3 induced mitochondria-mediated apoptosis via AMPK /ERK1/2 pathway and resisted autophagy-related ferroptosis via AMPK/mTOR pathway in hyperplastic prostate
by: Yan Li, et al.
Published: (2023-08-01)

Microbiota-derived tryptophan metabolism and AMPK/mTOR pathway mediate antidepressant-like effect of Shugan Hewei Decoction
by: Yingying Yue, et al.
Published: (2024-09-01)

PPARγ Plays an Important Role in Acute Hepatic Ischemia-Reperfusion Injury via AMPK/mTOR Pathway
by: Liwei Wu, et al.
Published: (2021-01-01)

Hesperetin Induces Autophagy and Delayed Apoptosis by Modulating the AMPK/Akt/mTOR Pathway in Human Leukemia Cells In Vitro
by: Ching-Yeh Lin, et al.
Published: (2023-02-01)

Trpm2 deficiency in microglia attenuates neuroinflammation during epileptogenesis by upregulating autophagy via the AMPK/mTOR pathway
by: Chen Chen, et al.
Published: (2023-10-01)

FSHR-mTOR-HIF1 signaling alleviates mouse follicles from AMPK-induced atresia
by: Longping Liu, et al.
Published: (2023-10-01)

Autophagy in Rat Müller Glial Cells Is Modulated by the Sirtuin 4/AMPK/mTOR Pathway and Induces Apoptosis under Oxidative Stress
by: Mengqi Qin, et al.
Published: (2022-08-01)

The lncRNA LINC01605 promotes the progression of pancreatic ductal adenocarcinoma by activating the mTOR signaling pathway
by: Yu-Heng Zhu, et al.
Published: (2024-07-01)

The mTOR pathway and integrating immune regulation.
by: Cobbold, S
Published: (2013)