NiCu magnetic nanoparticles: review of synthesis methods, surface functionalization approaches, and biomedical applications
Magnetic nanoparticles (MNPs) have attracted extensive interest in recent years because of their unique magnetic, electronic, catalytical, optical, and chemical properties. Lately, research on bimetallic MNPs based on nickel and copper (NiCu MNPs) gained momentum owing to their desired properties fo...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
De Gruyter
2018-04-01
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| Series: | Nanotechnology Reviews |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/ntrev-2017-0193 |
| _version_ | 1818941160998043648 |
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| author | Ban Irena Stergar Janja Maver Uroš |
| author_facet | Ban Irena Stergar Janja Maver Uroš |
| author_sort | Ban Irena |
| collection | DOAJ |
| description | Magnetic nanoparticles (MNPs) have attracted extensive interest in recent years because of their unique magnetic, electronic, catalytical, optical, and chemical properties. Lately, research on bimetallic MNPs based on nickel and copper (NiCu MNPs) gained momentum owing to their desired properties for use in biomedicine, such as their chemical stability, biocompatibility, and highly tunable magnetic properties by means of synthesis parameter tuning. The general interest of using NiCu MNPs in biomedical applications is still low, although it is steadily increasing as can be deduced from the number of related publications in the last years. When exposed to an alternating magnetic field (AMF), superparamagnetic particles (such as NiCu MNPs) generate heat by relaxation losses. Consequently, magnetic hyperthermia in cancer treatment seems to be their most promising application in medicine, although others are emerging as well, such as their use to guide potent drugs to the targeted site or to prolong their localization at a desired site in the body. This review is the first, to the best of our knowledge, that covers the available knowledge related to the preparation of NiCu MNPs using different methods, their resulting properties, and the already developed functionalization methods and that discusses everything mentioned in relation to their possible applicability in biomedicine. |
| first_indexed | 2024-12-20T06:51:08Z |
| format | Article |
| id | doaj.art-0174b62c2ae34a1e9cdc98976642414e |
| institution | Directory Open Access Journal |
| issn | 2191-9089 2191-9097 |
| language | English |
| last_indexed | 2024-12-20T06:51:08Z |
| publishDate | 2018-04-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Nanotechnology Reviews |
| spelling | doaj.art-0174b62c2ae34a1e9cdc98976642414e2022-12-21T19:49:31ZengDe GruyterNanotechnology Reviews2191-90892191-90972018-04-017218720710.1515/ntrev-2017-0193NiCu magnetic nanoparticles: review of synthesis methods, surface functionalization approaches, and biomedical applicationsBan Irena0Stergar Janja1Maver Uroš2Faculty of Chemistry and Chemical Engineering, Laboratory of Inorganic Chemistry, University of Maribor, Smetanova Ulica 17, SI-2000 Maribor, SloveniaFaculty of Chemistry and Chemical Engineering, Laboratory of Inorganic Chemistry, University of Maribor, Smetanova Ulica 17, SI-2000 Maribor, SloveniaFaculty of Medicine, Institute of Biomedical Sciences, University of Maribor, Taborska ulica 8, SI-2000 Maribor, SloveniaMagnetic nanoparticles (MNPs) have attracted extensive interest in recent years because of their unique magnetic, electronic, catalytical, optical, and chemical properties. Lately, research on bimetallic MNPs based on nickel and copper (NiCu MNPs) gained momentum owing to their desired properties for use in biomedicine, such as their chemical stability, biocompatibility, and highly tunable magnetic properties by means of synthesis parameter tuning. The general interest of using NiCu MNPs in biomedical applications is still low, although it is steadily increasing as can be deduced from the number of related publications in the last years. When exposed to an alternating magnetic field (AMF), superparamagnetic particles (such as NiCu MNPs) generate heat by relaxation losses. Consequently, magnetic hyperthermia in cancer treatment seems to be their most promising application in medicine, although others are emerging as well, such as their use to guide potent drugs to the targeted site or to prolong their localization at a desired site in the body. This review is the first, to the best of our knowledge, that covers the available knowledge related to the preparation of NiCu MNPs using different methods, their resulting properties, and the already developed functionalization methods and that discusses everything mentioned in relation to their possible applicability in biomedicine.https://doi.org/10.1515/ntrev-2017-0193biomedical applicationsmagnetic hyperthermiamagnetic nanoparticlesnicusynthesis |
| spellingShingle | Ban Irena Stergar Janja Maver Uroš NiCu magnetic nanoparticles: review of synthesis methods, surface functionalization approaches, and biomedical applications Nanotechnology Reviews biomedical applications magnetic hyperthermia magnetic nanoparticles nicu synthesis |
| title | NiCu magnetic nanoparticles: review of synthesis methods, surface functionalization approaches, and biomedical applications |
| title_full | NiCu magnetic nanoparticles: review of synthesis methods, surface functionalization approaches, and biomedical applications |
| title_fullStr | NiCu magnetic nanoparticles: review of synthesis methods, surface functionalization approaches, and biomedical applications |
| title_full_unstemmed | NiCu magnetic nanoparticles: review of synthesis methods, surface functionalization approaches, and biomedical applications |
| title_short | NiCu magnetic nanoparticles: review of synthesis methods, surface functionalization approaches, and biomedical applications |
| title_sort | nicu magnetic nanoparticles review of synthesis methods surface functionalization approaches and biomedical applications |
| topic | biomedical applications magnetic hyperthermia magnetic nanoparticles nicu synthesis |
| url | https://doi.org/10.1515/ntrev-2017-0193 |
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