On the surface effects of citrates on nano-apatites: evidence of a decreased hydrophilicity
Abstract The surface structure and hydrophilicity of synthetic nanocrystalline apatite with strongly bound citrates on their surface are here investigated at the molecular level, by combining advanced IR spectroscopy, microgravimetry and adsorption microcalorimetry. Citrate are found to form unident...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2017-08-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-017-09376-x |
| _version_ | 1818428062092492800 |
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| author | Pavlo Ivanchenko José Manuel Delgado-López Michele Iafisco Jaime Gómez-Morales Anna Tampieri Gianmario Martra Yuriy Sakhno |
| author_facet | Pavlo Ivanchenko José Manuel Delgado-López Michele Iafisco Jaime Gómez-Morales Anna Tampieri Gianmario Martra Yuriy Sakhno |
| author_sort | Pavlo Ivanchenko |
| collection | DOAJ |
| description | Abstract The surface structure and hydrophilicity of synthetic nanocrystalline apatite with strongly bound citrates on their surface are here investigated at the molecular level, by combining advanced IR spectroscopy, microgravimetry and adsorption microcalorimetry. Citrate are found to form unidentate-like and ionic-like complexes with surface Ca2+ ions, with a surface coverage closely resembling that present in bone apatite platelets (i.e., 1 molecule/(n nm)2, with n ranging between 1.4 and 1.6). These surface complexes are part of a hydrated non-apatitic surface layer with a sub-nanometre thickness. Noticeably, it is found that the hydrophilicity of the nanoparticles, measured in terms of adsorption of water molecules in the form of multilayers, decreases in a significant extent in relation to the presence of citrates, most likely because of the exposure toward the exterior of –CH2 groups. Our findings provide new insights on the surface properties of bio-inspired nano-apatites, which can be of great relevance for better understanding the role of citrate in determining important interfacial properties, such as hydrophobicity, of bone apatite platelets. The evaluation and comprehension of surface composition and structure is also of paramount interest to strictly control the functions of synthetic biomaterials, since their surface chemistry strongly affects the hosting tissue response. |
| first_indexed | 2024-12-14T14:55:39Z |
| format | Article |
| id | doaj.art-01847b95e57f4853a4fc8a6124cb77ba |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-12-14T14:55:39Z |
| publishDate | 2017-08-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-01847b95e57f4853a4fc8a6124cb77ba2022-12-21T22:56:59ZengNature PortfolioScientific Reports2045-23222017-08-017111010.1038/s41598-017-09376-xOn the surface effects of citrates on nano-apatites: evidence of a decreased hydrophilicityPavlo Ivanchenko0José Manuel Delgado-López1Michele Iafisco2Jaime Gómez-Morales3Anna Tampieri4Gianmario Martra5Yuriy Sakhno6Department of Chemistry and Interdepartmental Centre “Nanostructured Interfaces and Surfaces-NIS”, University of Torino, Via P. Giuria 7Laboratorio de Estudios Cristalográficos, IACT (CSIC-UGR), Avda. Las Palmeras 4Institute of Science and Technology for Ceramics (ISTEC), National Research Council (CNR), Via Granarolo 64Laboratorio de Estudios Cristalográficos, IACT (CSIC-UGR), Avda. Las Palmeras 4Institute of Science and Technology for Ceramics (ISTEC), National Research Council (CNR), Via Granarolo 64Department of Chemistry and Interdepartmental Centre “Nanostructured Interfaces and Surfaces-NIS”, University of Torino, Via P. Giuria 7Department of Chemistry and Interdepartmental Centre “Nanostructured Interfaces and Surfaces-NIS”, University of Torino, Via P. Giuria 7Abstract The surface structure and hydrophilicity of synthetic nanocrystalline apatite with strongly bound citrates on their surface are here investigated at the molecular level, by combining advanced IR spectroscopy, microgravimetry and adsorption microcalorimetry. Citrate are found to form unidentate-like and ionic-like complexes with surface Ca2+ ions, with a surface coverage closely resembling that present in bone apatite platelets (i.e., 1 molecule/(n nm)2, with n ranging between 1.4 and 1.6). These surface complexes are part of a hydrated non-apatitic surface layer with a sub-nanometre thickness. Noticeably, it is found that the hydrophilicity of the nanoparticles, measured in terms of adsorption of water molecules in the form of multilayers, decreases in a significant extent in relation to the presence of citrates, most likely because of the exposure toward the exterior of –CH2 groups. Our findings provide new insights on the surface properties of bio-inspired nano-apatites, which can be of great relevance for better understanding the role of citrate in determining important interfacial properties, such as hydrophobicity, of bone apatite platelets. The evaluation and comprehension of surface composition and structure is also of paramount interest to strictly control the functions of synthetic biomaterials, since their surface chemistry strongly affects the hosting tissue response.https://doi.org/10.1038/s41598-017-09376-x |
| spellingShingle | Pavlo Ivanchenko José Manuel Delgado-López Michele Iafisco Jaime Gómez-Morales Anna Tampieri Gianmario Martra Yuriy Sakhno On the surface effects of citrates on nano-apatites: evidence of a decreased hydrophilicity Scientific Reports |
| title | On the surface effects of citrates on nano-apatites: evidence of a decreased hydrophilicity |
| title_full | On the surface effects of citrates on nano-apatites: evidence of a decreased hydrophilicity |
| title_fullStr | On the surface effects of citrates on nano-apatites: evidence of a decreased hydrophilicity |
| title_full_unstemmed | On the surface effects of citrates on nano-apatites: evidence of a decreased hydrophilicity |
| title_short | On the surface effects of citrates on nano-apatites: evidence of a decreased hydrophilicity |
| title_sort | on the surface effects of citrates on nano apatites evidence of a decreased hydrophilicity |
| url | https://doi.org/10.1038/s41598-017-09376-x |
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