Diagnostic and treatment challenges in management of allergic fungal rhinosinusitis
Among infections pertaining to head and neck rhinosinusitis holds a significant position both with regard to the prevalence and morbidity. Allergic fungal rhinosinusitis (AFRS) was initially considered a counterpart of allergic bronchopulmonary aspergillosis when first diagnosed by Sa firstein in 19...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2017-01-01
|
| Series: | Indian Journal of Allergy Asthma and Immunology |
| Subjects: | |
| Online Access: | http://www.ijaai.in/article.asp?issn=0972-6691;year=2017;volume=31;issue=2;spage=38;epage=44;aulast=Singh |
| _version_ | 1819126802163957760 |
|---|---|
| author | Abhishek Bahadur Singh Rashmi Upadhyay Nitesh Tayal |
| author_facet | Abhishek Bahadur Singh Rashmi Upadhyay Nitesh Tayal |
| author_sort | Abhishek Bahadur Singh |
| collection | DOAJ |
| description | Among infections pertaining to head and neck rhinosinusitis holds a significant position both with regard to the prevalence and morbidity. Allergic fungal rhinosinusitis (AFRS) was initially considered a counterpart of allergic bronchopulmonary aspergillosis when first diagnosed by Sa firstein in 1976 due to its clinical presentations and seemingly similar pathogenesis. Initially only Aspergillus was known as the causative, but now various other fungal species are known to cause chronic rhinosinusitis; hence, the terminology allergic fungal sinusitis was preferred. Exposure to fungi results in similar as asthma in atopic individuals, but then, some nonatopic individuals may also present with similar symptoms. It has also been studied that the presence of serum immunoglobulin E does not ensure the presence of allergy. Till date, there are several controversies regarding pathogenesis, whether humoral or immune mediated, population at risk, variations in presentations, diagnostic parameters, and treatment protocols. In this review, we try to revisit and learn from past documented experiences to further our attempt toward better understanding of the disease process, its diagnosis, and management. |
| first_indexed | 2024-12-22T08:01:49Z |
| format | Article |
| id | doaj.art-0188344fc2194ae989771c36768b12b8 |
| institution | Directory Open Access Journal |
| issn | 0972-6691 |
| language | English |
| last_indexed | 2024-12-22T08:01:49Z |
| publishDate | 2017-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Allergy Asthma and Immunology |
| spelling | doaj.art-0188344fc2194ae989771c36768b12b82022-12-21T18:33:14ZengWolters Kluwer Medknow PublicationsIndian Journal of Allergy Asthma and Immunology0972-66912017-01-01312384410.4103/ijaai.ijaai_31_16Diagnostic and treatment challenges in management of allergic fungal rhinosinusitisAbhishek Bahadur SinghRashmi UpadhyayNitesh TayalAmong infections pertaining to head and neck rhinosinusitis holds a significant position both with regard to the prevalence and morbidity. Allergic fungal rhinosinusitis (AFRS) was initially considered a counterpart of allergic bronchopulmonary aspergillosis when first diagnosed by Sa firstein in 1976 due to its clinical presentations and seemingly similar pathogenesis. Initially only Aspergillus was known as the causative, but now various other fungal species are known to cause chronic rhinosinusitis; hence, the terminology allergic fungal sinusitis was preferred. Exposure to fungi results in similar as asthma in atopic individuals, but then, some nonatopic individuals may also present with similar symptoms. It has also been studied that the presence of serum immunoglobulin E does not ensure the presence of allergy. Till date, there are several controversies regarding pathogenesis, whether humoral or immune mediated, population at risk, variations in presentations, diagnostic parameters, and treatment protocols. In this review, we try to revisit and learn from past documented experiences to further our attempt toward better understanding of the disease process, its diagnosis, and management.http://www.ijaai.in/article.asp?issn=0972-6691;year=2017;volume=31;issue=2;spage=38;epage=44;aulast=SinghAllergic fungal rhinosinusitisasthmachronic rhinosinusitisserum immunoglobulin E |
| spellingShingle | Abhishek Bahadur Singh Rashmi Upadhyay Nitesh Tayal Diagnostic and treatment challenges in management of allergic fungal rhinosinusitis Indian Journal of Allergy Asthma and Immunology Allergic fungal rhinosinusitis asthma chronic rhinosinusitis serum immunoglobulin E |
| title | Diagnostic and treatment challenges in management of allergic fungal rhinosinusitis |
| title_full | Diagnostic and treatment challenges in management of allergic fungal rhinosinusitis |
| title_fullStr | Diagnostic and treatment challenges in management of allergic fungal rhinosinusitis |
| title_full_unstemmed | Diagnostic and treatment challenges in management of allergic fungal rhinosinusitis |
| title_short | Diagnostic and treatment challenges in management of allergic fungal rhinosinusitis |
| title_sort | diagnostic and treatment challenges in management of allergic fungal rhinosinusitis |
| topic | Allergic fungal rhinosinusitis asthma chronic rhinosinusitis serum immunoglobulin E |
| url | http://www.ijaai.in/article.asp?issn=0972-6691;year=2017;volume=31;issue=2;spage=38;epage=44;aulast=Singh |
| work_keys_str_mv | AT abhishekbahadursingh diagnosticandtreatmentchallengesinmanagementofallergicfungalrhinosinusitis AT rashmiupadhyay diagnosticandtreatmentchallengesinmanagementofallergicfungalrhinosinusitis AT niteshtayal diagnosticandtreatmentchallengesinmanagementofallergicfungalrhinosinusitis |