Primary Extra Renal Papillary Renal Cell Carcinoma Masquerading as A Metastatic Carcinoma: A Unique Case with Dual Malignancies
A 50-year-old male presented with abdominal pain, pain during defaecation, constipation, bleeding per rectum for 2 months. Colonoscopy showed an ulcero-proliferative growth, that is 2.5 cm from anal verge. Further PET-CT confirmed the growth in the lower rectum with mesorectal fat stranding and an i...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Asian Medical Press Ltd.(H.K.)
2023-09-01
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| Series: | Annals of Urologic Oncology |
| Subjects: | |
| Online Access: | http://auo.asmepress.com/articles/new-96-561.html |
| _version_ | 1797682845680926720 |
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| author | Sivaranjani Selvaraj Akkamahadevi Patil Champaka. G Usha Amirtham |
| author_facet | Sivaranjani Selvaraj Akkamahadevi Patil Champaka. G Usha Amirtham |
| author_sort | Sivaranjani Selvaraj |
| collection | DOAJ |
| description | A 50-year-old male presented with abdominal pain, pain during defaecation, constipation, bleeding per rectum for 2 months. Colonoscopy showed an ulcero-proliferative growth, that is 2.5 cm from anal verge. Further PET-CT confirmed the growth in the lower rectum with mesorectal fat stranding and an irregular, lobulated, encapsulated solid-cystic mass in right perinephric fat, separated from the kidney (suggestive of metastasis), with intact bilateral kidneys. Biopsy of the rectum revealed an adenocarcinoma and biopsy of right perinephric mass revealed a papillary neoplasm. Following which abdominoperineal resection with perinephric mass excision was performed, due to encapsulation of mass. Histopathological evaluation and further immunohistochemistry performed was positive for vimentin, AMACR, CD10 and negative for other markers to rule out metastasis of either. This led to the diagnosis of synchronous primaries i.e., Extra-renal papillary renal cell carcinoma and adenocarcinoma of rectum. |
| first_indexed | 2024-03-12T00:05:48Z |
| format | Article |
| id | doaj.art-018d3f0b6bc546429a1eb8070f485329 |
| institution | Directory Open Access Journal |
| issn | 2617-7765 2617-7773 |
| language | English |
| last_indexed | 2024-03-12T00:05:48Z |
| publishDate | 2023-09-01 |
| publisher | Asian Medical Press Ltd.(H.K.) |
| record_format | Article |
| series | Annals of Urologic Oncology |
| spelling | doaj.art-018d3f0b6bc546429a1eb8070f4853292023-09-17T01:35:15ZengAsian Medical Press Ltd.(H.K.)Annals of Urologic Oncology2617-77652617-77732023-09-01610.32948/auo.2023.09.10Primary Extra Renal Papillary Renal Cell Carcinoma Masquerading as A Metastatic Carcinoma: A Unique Case with Dual MalignanciesSivaranjani Selvaraj0 Akkamahadevi Patil1Champaka. G2Usha Amirtham3Department of Pathology, Kidwai memorial institute of oncology, Bengaluru, India.Department of Pathology, Kidwai memorial institute of oncology, Bengaluru, India.Department of Pathology, Kidwai memorial institute of oncology, Bengaluru, India.Department of Pathology, Kidwai memorial institute of oncology, Bengaluru, India.A 50-year-old male presented with abdominal pain, pain during defaecation, constipation, bleeding per rectum for 2 months. Colonoscopy showed an ulcero-proliferative growth, that is 2.5 cm from anal verge. Further PET-CT confirmed the growth in the lower rectum with mesorectal fat stranding and an irregular, lobulated, encapsulated solid-cystic mass in right perinephric fat, separated from the kidney (suggestive of metastasis), with intact bilateral kidneys. Biopsy of the rectum revealed an adenocarcinoma and biopsy of right perinephric mass revealed a papillary neoplasm. Following which abdominoperineal resection with perinephric mass excision was performed, due to encapsulation of mass. Histopathological evaluation and further immunohistochemistry performed was positive for vimentin, AMACR, CD10 and negative for other markers to rule out metastasis of either. This led to the diagnosis of synchronous primaries i.e., Extra-renal papillary renal cell carcinoma and adenocarcinoma of rectum.http://auo.asmepress.com/articles/new-96-561.htmlrenal cell carcinomaextra-renal renal cell carcinomapapillarymetastasisheterotopic kidneysynchronous tumorsdual malignancies |
| spellingShingle | Sivaranjani Selvaraj Akkamahadevi Patil Champaka. G Usha Amirtham Primary Extra Renal Papillary Renal Cell Carcinoma Masquerading as A Metastatic Carcinoma: A Unique Case with Dual Malignancies Annals of Urologic Oncology renal cell carcinoma extra-renal renal cell carcinoma papillary metastasis heterotopic kidney synchronous tumors dual malignancies |
| title | Primary Extra Renal Papillary Renal Cell Carcinoma Masquerading as A Metastatic Carcinoma: A Unique Case with Dual Malignancies |
| title_full | Primary Extra Renal Papillary Renal Cell Carcinoma Masquerading as A Metastatic Carcinoma: A Unique Case with Dual Malignancies |
| title_fullStr | Primary Extra Renal Papillary Renal Cell Carcinoma Masquerading as A Metastatic Carcinoma: A Unique Case with Dual Malignancies |
| title_full_unstemmed | Primary Extra Renal Papillary Renal Cell Carcinoma Masquerading as A Metastatic Carcinoma: A Unique Case with Dual Malignancies |
| title_short | Primary Extra Renal Papillary Renal Cell Carcinoma Masquerading as A Metastatic Carcinoma: A Unique Case with Dual Malignancies |
| title_sort | primary extra renal papillary renal cell carcinoma masquerading as a metastatic carcinoma a unique case with dual malignancies |
| topic | renal cell carcinoma extra-renal renal cell carcinoma papillary metastasis heterotopic kidney synchronous tumors dual malignancies |
| url | http://auo.asmepress.com/articles/new-96-561.html |
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