Occurrence of paratesticular ganglioneuroma 18 years after concurrent adrenal ganglioneuroma and papillary thyroid carcinoma – a case report
Abstract Background Ganglioneuromas (GNs) are composed of mature ganglion cells and Schwann cells with a fibrous stroma; GNs are most often observed in children and young adults. The majority of non-cranial GNs are located in the retroperitoneum and posterior mediastinum. Other reported rare sites i...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2019-12-01
|
| Series: | BMC Cancer |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12885-019-6440-4 |
| _version_ | 1818427568109387776 |
|---|---|
| author | Chu-Wen Fang Jyh-Seng Wang Tony T. Wu Jen-Tai Lin |
| author_facet | Chu-Wen Fang Jyh-Seng Wang Tony T. Wu Jen-Tai Lin |
| author_sort | Chu-Wen Fang |
| collection | DOAJ |
| description | Abstract Background Ganglioneuromas (GNs) are composed of mature ganglion cells and Schwann cells with a fibrous stroma; GNs are most often observed in children and young adults. The majority of non-cranial GNs are located in the retroperitoneum and posterior mediastinum. Other reported rare sites include the adrenal gland, small intestine, colon and urinary bladder. However, para-testicular GNs are even more rare. Case presentation Herein, we report the case of a patient with concurrent adrenal GN and thyroid papillary carcinoma who developed paratesticular GN eighteen years later. Conclusions We conclude that there is an association among papillary thyroid carcinoma, GN and MEN2 syndromes. This case report may provide important information for the proposed association. However, further studies are required. |
| first_indexed | 2024-12-14T14:47:47Z |
| format | Article |
| id | doaj.art-019046c2464149ac826aacbb4bd6ea90 |
| institution | Directory Open Access Journal |
| issn | 1471-2407 |
| language | English |
| last_indexed | 2024-12-14T14:47:47Z |
| publishDate | 2019-12-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Cancer |
| spelling | doaj.art-019046c2464149ac826aacbb4bd6ea902022-12-21T22:57:14ZengBMCBMC Cancer1471-24072019-12-011911610.1186/s12885-019-6440-4Occurrence of paratesticular ganglioneuroma 18 years after concurrent adrenal ganglioneuroma and papillary thyroid carcinoma – a case reportChu-Wen Fang0Jyh-Seng Wang1Tony T. Wu2Jen-Tai Lin3Department of Surgery, Kaohsiung Veterans General HospitalDepartment of Pathology, Kaohsiung Veterans General HospitalDivision of Urology, Department of Surgery, Kaohsiung Veterans General HospitalDivision of Urology, Department of Surgery, Kaohsiung Veterans General HospitalAbstract Background Ganglioneuromas (GNs) are composed of mature ganglion cells and Schwann cells with a fibrous stroma; GNs are most often observed in children and young adults. The majority of non-cranial GNs are located in the retroperitoneum and posterior mediastinum. Other reported rare sites include the adrenal gland, small intestine, colon and urinary bladder. However, para-testicular GNs are even more rare. Case presentation Herein, we report the case of a patient with concurrent adrenal GN and thyroid papillary carcinoma who developed paratesticular GN eighteen years later. Conclusions We conclude that there is an association among papillary thyroid carcinoma, GN and MEN2 syndromes. This case report may provide important information for the proposed association. However, further studies are required.https://doi.org/10.1186/s12885-019-6440-4GanglioneuromaPapillary thyroid carcinoma (PCT)Paratesticular tumourMultiple endocrine neoplasm (MEN)RET |
| spellingShingle | Chu-Wen Fang Jyh-Seng Wang Tony T. Wu Jen-Tai Lin Occurrence of paratesticular ganglioneuroma 18 years after concurrent adrenal ganglioneuroma and papillary thyroid carcinoma – a case report BMC Cancer Ganglioneuroma Papillary thyroid carcinoma (PCT) Paratesticular tumour Multiple endocrine neoplasm (MEN) RET |
| title | Occurrence of paratesticular ganglioneuroma 18 years after concurrent adrenal ganglioneuroma and papillary thyroid carcinoma – a case report |
| title_full | Occurrence of paratesticular ganglioneuroma 18 years after concurrent adrenal ganglioneuroma and papillary thyroid carcinoma – a case report |
| title_fullStr | Occurrence of paratesticular ganglioneuroma 18 years after concurrent adrenal ganglioneuroma and papillary thyroid carcinoma – a case report |
| title_full_unstemmed | Occurrence of paratesticular ganglioneuroma 18 years after concurrent adrenal ganglioneuroma and papillary thyroid carcinoma – a case report |
| title_short | Occurrence of paratesticular ganglioneuroma 18 years after concurrent adrenal ganglioneuroma and papillary thyroid carcinoma – a case report |
| title_sort | occurrence of paratesticular ganglioneuroma 18 years after concurrent adrenal ganglioneuroma and papillary thyroid carcinoma a case report |
| topic | Ganglioneuroma Papillary thyroid carcinoma (PCT) Paratesticular tumour Multiple endocrine neoplasm (MEN) RET |
| url | https://doi.org/10.1186/s12885-019-6440-4 |
| work_keys_str_mv | AT chuwenfang occurrenceofparatesticularganglioneuroma18yearsafterconcurrentadrenalganglioneuromaandpapillarythyroidcarcinomaacasereport AT jyhsengwang occurrenceofparatesticularganglioneuroma18yearsafterconcurrentadrenalganglioneuromaandpapillarythyroidcarcinomaacasereport AT tonytwu occurrenceofparatesticularganglioneuroma18yearsafterconcurrentadrenalganglioneuromaandpapillarythyroidcarcinomaacasereport AT jentailin occurrenceofparatesticularganglioneuroma18yearsafterconcurrentadrenalganglioneuromaandpapillarythyroidcarcinomaacasereport |