Precise heteroatom doping determines aqueous solubility and self-assembly behaviors for polycyclic aromatic skeletons

Enhancing the hydrophilicity of hydrophobic molecular scaffolds allows to increase their aqueous solubility and therefore their usability for a range of applications. Here, N/O heteroatom doping of polycyclic aromatic hydrocarbons is shown to switch the skeleton from hydrophobic to hydrophilic, enha...

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Main Authors: Kang Li, Jia-Min Hu, Wei-Min Qin, Jing Guo, Yue-Peng Cai
Format: Article
Language:English
Published: Nature Portfolio 2022-08-01
Series:Communications Chemistry
Online Access:https://doi.org/10.1038/s42004-022-00724-1
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author Kang Li
Jia-Min Hu
Wei-Min Qin
Jing Guo
Yue-Peng Cai
author_facet Kang Li
Jia-Min Hu
Wei-Min Qin
Jing Guo
Yue-Peng Cai
author_sort Kang Li
collection DOAJ
description Enhancing the hydrophilicity of hydrophobic molecular scaffolds allows to increase their aqueous solubility and therefore their usability for a range of applications. Here, N/O heteroatom doping of polycyclic aromatic hydrocarbons is shown to switch the skeleton from hydrophobic to hydrophilic, enhancing aqueous solubility and facilitating self-assembly in water.
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spelling doaj.art-019422ae1a8a49b58f25d342a8625f772022-12-22T04:23:59ZengNature PortfolioCommunications Chemistry2399-36692022-08-01511710.1038/s42004-022-00724-1Precise heteroatom doping determines aqueous solubility and self-assembly behaviors for polycyclic aromatic skeletonsKang Li0Jia-Min Hu1Wei-Min Qin2Jing Guo3Yue-Peng Cai4School of Chemistry, South China Normal UniversitySchool of Chemistry, South China Normal UniversitySchool of Chemistry, South China Normal UniversitySchool of Chemistry, Sun Yat-Sen UniversitySchool of Chemistry, South China Normal UniversityEnhancing the hydrophilicity of hydrophobic molecular scaffolds allows to increase their aqueous solubility and therefore their usability for a range of applications. Here, N/O heteroatom doping of polycyclic aromatic hydrocarbons is shown to switch the skeleton from hydrophobic to hydrophilic, enhancing aqueous solubility and facilitating self-assembly in water.https://doi.org/10.1038/s42004-022-00724-1
spellingShingle Kang Li
Jia-Min Hu
Wei-Min Qin
Jing Guo
Yue-Peng Cai
Precise heteroatom doping determines aqueous solubility and self-assembly behaviors for polycyclic aromatic skeletons
Communications Chemistry
title Precise heteroatom doping determines aqueous solubility and self-assembly behaviors for polycyclic aromatic skeletons
title_full Precise heteroatom doping determines aqueous solubility and self-assembly behaviors for polycyclic aromatic skeletons
title_fullStr Precise heteroatom doping determines aqueous solubility and self-assembly behaviors for polycyclic aromatic skeletons
title_full_unstemmed Precise heteroatom doping determines aqueous solubility and self-assembly behaviors for polycyclic aromatic skeletons
title_short Precise heteroatom doping determines aqueous solubility and self-assembly behaviors for polycyclic aromatic skeletons
title_sort precise heteroatom doping determines aqueous solubility and self assembly behaviors for polycyclic aromatic skeletons
url https://doi.org/10.1038/s42004-022-00724-1
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AT jingguo preciseheteroatomdopingdeterminesaqueoussolubilityandselfassemblybehaviorsforpolycyclicaromaticskeletons
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