Chlorogenic Acid Inhibits Ceramide Accumulation to Restrain Hepatic Glucagon Response

Chlorogenic Acid Inhibits Ceramide Accumulation to Restrain Hepatic Glucagon Response

Chlorogenic acid (CGA), a dietary natural phenolic acid, has been widely reported to regulate glucose and lipid metabolism. However, the protective effects and the underlying mechanisms of CGA on glucagon-induced hepatic glucose production remain largely uncharacterized. Herein, we investigated the...

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Bibliographic Details
Main Authors: Na Xiao, Tengfei Zhang, Mingli Han, Dan Tian, Jiawei Liu, Shan Li, Lele Yang, Guojun Pan
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Nutrients
Subjects:
chlorogenic acid
glucagon
gluconeogenesis
ceramide
Akt/FoxO1
Online Access:https://www.mdpi.com/2072-6643/15/14/3173

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