Ripe Tomato Saponin Esculeoside A and Sapogenol Esculeogenin A Suppress CD4+ T Lymphocyte Activation by Modulation of Th2/Th1/Treg Differentiation

Ripe Tomato Saponin Esculeoside A and Sapogenol Esculeogenin A Suppress CD4+ T Lymphocyte Activation by Modulation of Th2/Th1/Treg Differentiation

We report that esculeoside A (EsA), a glycoside and a major component in ripe tomato fruit, ameliorated experimental dermatitis in mice. However, the underlying immunologic molecular mechanisms are unknown. The present study examined its underlying immune nutrition mechanism using concanavalin A (Co...

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Bibliographic Details
Main Authors:	Jian-Rong Zhou, Rie Yamada, Erina Huruiti, Nozomi Kitahara, Honami Nakamura, Jun Fang, Toshihiro Nohara, Kazumi Yokomizo
Format:	Article
Language:	English
Published:	MDPI AG 2022-05-01
Series:	Nutrients
Subjects:	CD4+ T lymphocyte esculeogenin A (Esg-A) esculeoside A (EsA) ripe tomato fruit saponin Th1 Th2
Online Access:	https://www.mdpi.com/2072-6643/14/10/2021

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