Targeted lipid nanoparticle delivery of calcitriol to human monocyte-derived macrophages in vitro and in vivo: investigation of the anti-inflammatory effects of calcitriol

Targeted lipid nanoparticle delivery of calcitriol to human monocyte-derived macrophages in vitro and in vivo: investigation of the anti-inflammatory effects of calcitriol

Aisha Rafique,1 Anders Etzerodt,2 Jonas H Graversen,3 Søren K Moestrup,3 Frederik Dagnæs-Hansen,2 Holger Jon Møller1 1Department of Clinical Biochemistry, Aarhus University Hospital, Aarhus, Denmark; 2Institute of Biomedicine, Aarhus University, Aarhus, Denmark; 3Dep...

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Bibliographic Details
Main Authors: Rafique A, Etzerodt A, Graversen JH, Moestrup SK, Dagnæs-Hansen F, Møller HJ
Format: Article
Language:English
Published: Dove Medical Press 2019-04-01
Series:International Journal of Nanomedicine
Subjects:
Macrophages
targeted drug delivery
calcitriol
TNF-α
HLA-DR
CD80
IL-6
NF-kB
MCP-1
CD163
mRNA gene expression
ELISA
flow cytometry
confocal microscopy
lipid nanoparticles
low-grade inflammation
immunomodulation
in vivo imaging
Online Access:https://www.dovepress.com/targeted-lipid-nanoparticle-delivery-of-calcitriol-to-human-monocyte-d-peer-reviewed-article-IJN

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