The VP3 Protein of Bluetongue Virus Associates with the MAVS Complex and Interferes with the RIG-I-Signaling Pathway

The VP3 Protein of Bluetongue Virus Associates with the MAVS Complex and Interferes with the RIG-I-Signaling Pathway

Bluetongue virus (BTV), an arbovirus transmitted by <i>Culicoides</i> biting midges, is a major concern of wild and domestic ruminants. While BTV induces type I interferon (alpha/beta interferon [IFN-α/β]) production in infected cells, several reports have described evasion strategies el...

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Bibliographic Details
Main Authors: Marie Pourcelot, Rayane Amaral Moraes, Aurore Fablet, Emmanuel Bréard, Corinne Sailleau, Cyril Viarouge, Lydie Postic, Stéphan Zientara, Grégory Caignard, Damien Vitour
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Viruses
Subjects:
Bluetongue virus
VP3
MAVS
IKKε
type-I interferons
virus–host interactions
Online Access:https://www.mdpi.com/1999-4915/13/2/230

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