Survival of women with cervical cancer in East Africa: a systematic review and meta-analysis
Background The prognosis for cervical cancer varies greatly between nations. The disparity in cancer survival rates within nations is largely a result of disparities in public knowledge, the accessibility of cancer services, diagnosis and treatment. The purpose of this systematic review and meta-ana...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2023-12-01
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| Series: | Journal of Obstetrics and Gynaecology |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/01443615.2023.2253308 |
| _version_ | 1797640979993329664 |
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| author | Roza Kassa Yang Irene Edom Woldetsadik Eshetu Kidane Melinda Higgins Tariku Dejene Jessica Wells |
| author_facet | Roza Kassa Yang Irene Edom Woldetsadik Eshetu Kidane Melinda Higgins Tariku Dejene Jessica Wells |
| author_sort | Roza Kassa |
| collection | DOAJ |
| description | Background The prognosis for cervical cancer varies greatly between nations. The disparity in cancer survival rates within nations is largely a result of disparities in public knowledge, the accessibility of cancer services, diagnosis and treatment. The purpose of this systematic review and meta-analysis is to assess the survival rate and associated factors among cervical cancer patients in East Africa. Methods Literature search was carried out using Google scholar, PubMed/Medline, Embase and CINHAL. Covidence, a web-based program, was used to import studies for review process. PRISMA guidelines were followed. A total of 110 abstracts were identified from electronic sources. There were five duplicate articles removed. We looked at 105 papers’ abstracts and titles, and we excluded 78 of them because they did not fit our inclusion criteria. We conducted a full-text analysis of the remaining 27 papers, leaving out 14 researches that did not fit our inclusion requirements. For final review, 13 studies were included. Using the Joanna Briggs Institute (JBI) assessment checklist, methodological quality was evaluated. Results The included articles were cohort studies. They were conducted in Ethiopia, Uganda, Zimbabwe, Kenya, Sudan, Tanzania and Rwanda. One-year, two-year, three-year, four-year and five-year overall survival rates ranged from 67% to 92%, 55% to 84%, 44% to 53%, 32% to 47%, and 26% to 43%, respectively. Conclusions The pooled one-year, two-year, three-year, four-year and five-year survival rates of cervical cancer patients in East Africa were 84%, 71%, 50%, 39% and 36%, respectively. HIV status, late presentation, treatment modalities, older age and presence of comorbidities were the most commonly mentioned prognostic factors for survival. PROSPERO Registration number CRD42023402551 |
| first_indexed | 2024-03-11T13:38:00Z |
| format | Article |
| id | doaj.art-019dfa424db848e3a914916066b8092e |
| institution | Directory Open Access Journal |
| issn | 0144-3615 1364-6893 |
| language | English |
| last_indexed | 2024-03-11T13:38:00Z |
| publishDate | 2023-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Journal of Obstetrics and Gynaecology |
| spelling | doaj.art-019dfa424db848e3a914916066b8092e2023-11-02T13:56:29ZengTaylor & Francis GroupJournal of Obstetrics and Gynaecology0144-36151364-68932023-12-0143210.1080/01443615.2023.22533082253308Survival of women with cervical cancer in East Africa: a systematic review and meta-analysisRoza Kassa0Yang Irene1Edom Woldetsadik2Eshetu Kidane3Melinda Higgins4Tariku Dejene5Jessica Wells6Department of Midwifery, School of Nursing & Midwifery, College of Health Sciences, Addis Ababa UniversityNell Hodgson Woodruff School of Nursing, Emory UniversityDepartment of Oncology, School of Medicine, College of Health Sciences, Addis Ababa UniversityDepartment of Preventive Medicine, School of Public Health, College of Health Sciences, Addis Ababa UniversityNell Hodgson Woodruff School of Nursing, Emory UniversityCollege of Developmental Study, Center for Population Studies, Addis Ababa UniversityNell Hodgson Woodruff School of Nursing, Emory UniversityBackground The prognosis for cervical cancer varies greatly between nations. The disparity in cancer survival rates within nations is largely a result of disparities in public knowledge, the accessibility of cancer services, diagnosis and treatment. The purpose of this systematic review and meta-analysis is to assess the survival rate and associated factors among cervical cancer patients in East Africa. Methods Literature search was carried out using Google scholar, PubMed/Medline, Embase and CINHAL. Covidence, a web-based program, was used to import studies for review process. PRISMA guidelines were followed. A total of 110 abstracts were identified from electronic sources. There were five duplicate articles removed. We looked at 105 papers’ abstracts and titles, and we excluded 78 of them because they did not fit our inclusion criteria. We conducted a full-text analysis of the remaining 27 papers, leaving out 14 researches that did not fit our inclusion requirements. For final review, 13 studies were included. Using the Joanna Briggs Institute (JBI) assessment checklist, methodological quality was evaluated. Results The included articles were cohort studies. They were conducted in Ethiopia, Uganda, Zimbabwe, Kenya, Sudan, Tanzania and Rwanda. One-year, two-year, three-year, four-year and five-year overall survival rates ranged from 67% to 92%, 55% to 84%, 44% to 53%, 32% to 47%, and 26% to 43%, respectively. Conclusions The pooled one-year, two-year, three-year, four-year and five-year survival rates of cervical cancer patients in East Africa were 84%, 71%, 50%, 39% and 36%, respectively. HIV status, late presentation, treatment modalities, older age and presence of comorbidities were the most commonly mentioned prognostic factors for survival. PROSPERO Registration number CRD42023402551http://dx.doi.org/10.1080/01443615.2023.2253308cervical cancersurvival rateeast africa |
| spellingShingle | Roza Kassa Yang Irene Edom Woldetsadik Eshetu Kidane Melinda Higgins Tariku Dejene Jessica Wells Survival of women with cervical cancer in East Africa: a systematic review and meta-analysis Journal of Obstetrics and Gynaecology cervical cancer survival rate east africa |
| title | Survival of women with cervical cancer in East Africa: a systematic review and meta-analysis |
| title_full | Survival of women with cervical cancer in East Africa: a systematic review and meta-analysis |
| title_fullStr | Survival of women with cervical cancer in East Africa: a systematic review and meta-analysis |
| title_full_unstemmed | Survival of women with cervical cancer in East Africa: a systematic review and meta-analysis |
| title_short | Survival of women with cervical cancer in East Africa: a systematic review and meta-analysis |
| title_sort | survival of women with cervical cancer in east africa a systematic review and meta analysis |
| topic | cervical cancer survival rate east africa |
| url | http://dx.doi.org/10.1080/01443615.2023.2253308 |
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