A disintegrin and metalloproteinase domain 9 facilitates SARS-CoV-2 entry into cells with low ACE2 expression

A disintegrin and metalloproteinase domain 9 facilitates SARS-CoV-2 entry into cells with low ACE2 expression

ABSTRACT Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiological agent of the Coronavirus disease-19 (COVID-19) pandemic, utilizes angiotensin-converting enzyme 2 (ACE2) as a receptor for virus infection. However, the expression pattern of ACE2 does not coincide with the tissue...

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Bibliographic Details
Main Authors: Ivonne Melano, Wei-Chung Cheng, Li-Lan Kuo, Yuag-Meng Liu, Yu Chi Chou, Mien-Chie Hung, Michael M. C. Lai, Yuh-Pyng Sher, Wen-Chi Su
Format: Article
Language:English
Published: American Society for Microbiology 2023-10-01
Series:Microbiology Spectrum
Subjects:
SARS-CoV-2
coronavirus
virus entry
virus-host interactions
infectious disease
Online Access:https://journals.asm.org/doi/10.1128/spectrum.03854-22

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