Siglec Receptors Modulate Dendritic Cell Activation and Antigen Presentation to T Cells in Cancer

Siglec Receptors Modulate Dendritic Cell Activation and Antigen Presentation to T Cells in Cancer

Interactions between sialylated glycans and sialic acid-binding immunoglobulin-like lectin (Siglec) receptors have been recently described as potential new immune checkpoint that can be targeted to improve anticancer immunity. Myeloid cells have been reported to express a wide range of different Sig...

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Bibliographic Details
Main Authors: Jinyu Wang, Michela Manni, Anne Bärenwaldt, Ronja Wieboldt, Nicole Kirchhammer, Robert Ivanek, Michal Stanczak, Alfred Zippelius, David König, Natalia Rodrigues Manutano, Heinz Läubli
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
sialic acid
tumor immunology
glyco-immune checkpoint
antigen
antigen processing
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.828916/full

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