Effect of preoperative vitamin D deficiency on functional outcomes after high tibial osteotomy: a retrospective case control study
Abstract Background This study aimed to evaluate the effects of vitamin D deficiency on the functional outcomes following a high tibial osteotomy (HTO). Methods Clinical data of 209 patients (327 knees) who underwent HTO done by a single surgeon were retrospectively registered for the study. Ninety-...
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| Format: | Article |
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BMC
2020-04-01
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| Series: | BMC Musculoskeletal Disorders |
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| Online Access: | http://link.springer.com/article/10.1186/s12891-020-03295-1 |
| _version_ | 1818282384501506048 |
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| author | Wonchul Choi Jae Hwa Kim Seong-Eun Byun Han-Seung Ryu David Rojas |
| author_facet | Wonchul Choi Jae Hwa Kim Seong-Eun Byun Han-Seung Ryu David Rojas |
| author_sort | Wonchul Choi |
| collection | DOAJ |
| description | Abstract Background This study aimed to evaluate the effects of vitamin D deficiency on the functional outcomes following a high tibial osteotomy (HTO). Methods Clinical data of 209 patients (327 knees) who underwent HTO done by a single surgeon were retrospectively registered for the study. Ninety-four patients (94 knees) who underwent HTO were analyzed. Patients were assigned into two groups according to their preoperative serum vitamin D levels (D- Deficiency and S- Sufficient); < 20 ng/ml (group D, N = 48) and ≥ 20 ng/ml (group S, N = 46) respectively. A subjective form of International Knee Documentation Committee (IKDC) score, mechanical alignment, and cartilage status before and 1 year following HTO were studied between groups. Results The mean postoperative IKDC score was significantly higher in group S (p = 0.012). Moreover, the difference of IKDC score between pre- and post- HTO was also significantly higher in group S (p = 0.006). Preoperative vitamin D level and IKDC score did not show a significant correlation. Serum vitamin D level was found to be moderately correlated to postoperative IKDC score (r = 0.342 and, p = 0.001). A moderately positive correlation between serum vitamin D level and improvement of IKDC score following osteotomy was appreciated (r = 0.381 and, p < 0.001). Conclusion Patients with vitamin D deficiency had less satisfactory functional outcomes within 1 year from HTO surgery. Our results suggest that preoperative serum vitamin D level is one of the factors affecting the outcome after HTO. We recommended analyzing serum vitamin D levels as part of the routine workup in patients undergoing HTO. |
| first_indexed | 2024-12-13T00:20:10Z |
| format | Article |
| id | doaj.art-01a673d21713433cab0dc5296d528938 |
| institution | Directory Open Access Journal |
| issn | 1471-2474 |
| language | English |
| last_indexed | 2024-12-13T00:20:10Z |
| publishDate | 2020-04-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Musculoskeletal Disorders |
| spelling | doaj.art-01a673d21713433cab0dc5296d5289382022-12-22T00:05:37ZengBMCBMC Musculoskeletal Disorders1471-24742020-04-012111710.1186/s12891-020-03295-1Effect of preoperative vitamin D deficiency on functional outcomes after high tibial osteotomy: a retrospective case control studyWonchul Choi0Jae Hwa Kim1Seong-Eun Byun2Han-Seung Ryu3David Rojas4Department of Orthopaedic Surgery, CHA Bundang Medical Center, CHA UniversityDepartment of Orthopaedic Surgery, CHA Bundang Medical Center, CHA UniversityDepartment of Orthopaedic Surgery, CHA Bundang Medical Center, CHA UniversityDepartment of Orthopaedic Surgery, CHA Bundang Medical Center, CHA UniversityDepartment of Orthopaedic Surgery, Denver Health Medical CenterAbstract Background This study aimed to evaluate the effects of vitamin D deficiency on the functional outcomes following a high tibial osteotomy (HTO). Methods Clinical data of 209 patients (327 knees) who underwent HTO done by a single surgeon were retrospectively registered for the study. Ninety-four patients (94 knees) who underwent HTO were analyzed. Patients were assigned into two groups according to their preoperative serum vitamin D levels (D- Deficiency and S- Sufficient); < 20 ng/ml (group D, N = 48) and ≥ 20 ng/ml (group S, N = 46) respectively. A subjective form of International Knee Documentation Committee (IKDC) score, mechanical alignment, and cartilage status before and 1 year following HTO were studied between groups. Results The mean postoperative IKDC score was significantly higher in group S (p = 0.012). Moreover, the difference of IKDC score between pre- and post- HTO was also significantly higher in group S (p = 0.006). Preoperative vitamin D level and IKDC score did not show a significant correlation. Serum vitamin D level was found to be moderately correlated to postoperative IKDC score (r = 0.342 and, p = 0.001). A moderately positive correlation between serum vitamin D level and improvement of IKDC score following osteotomy was appreciated (r = 0.381 and, p < 0.001). Conclusion Patients with vitamin D deficiency had less satisfactory functional outcomes within 1 year from HTO surgery. Our results suggest that preoperative serum vitamin D level is one of the factors affecting the outcome after HTO. We recommended analyzing serum vitamin D levels as part of the routine workup in patients undergoing HTO.http://link.springer.com/article/10.1186/s12891-020-03295-1High tibial osteotomyMedial open wedge high tibial osteotomyOsteoarthritisVitamin D25-hydroxy vitamin DFunctional outcome |
| spellingShingle | Wonchul Choi Jae Hwa Kim Seong-Eun Byun Han-Seung Ryu David Rojas Effect of preoperative vitamin D deficiency on functional outcomes after high tibial osteotomy: a retrospective case control study BMC Musculoskeletal Disorders High tibial osteotomy Medial open wedge high tibial osteotomy Osteoarthritis Vitamin D 25-hydroxy vitamin D Functional outcome |
| title | Effect of preoperative vitamin D deficiency on functional outcomes after high tibial osteotomy: a retrospective case control study |
| title_full | Effect of preoperative vitamin D deficiency on functional outcomes after high tibial osteotomy: a retrospective case control study |
| title_fullStr | Effect of preoperative vitamin D deficiency on functional outcomes after high tibial osteotomy: a retrospective case control study |
| title_full_unstemmed | Effect of preoperative vitamin D deficiency on functional outcomes after high tibial osteotomy: a retrospective case control study |
| title_short | Effect of preoperative vitamin D deficiency on functional outcomes after high tibial osteotomy: a retrospective case control study |
| title_sort | effect of preoperative vitamin d deficiency on functional outcomes after high tibial osteotomy a retrospective case control study |
| topic | High tibial osteotomy Medial open wedge high tibial osteotomy Osteoarthritis Vitamin D 25-hydroxy vitamin D Functional outcome |
| url | http://link.springer.com/article/10.1186/s12891-020-03295-1 |
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