Comparison of Structure and Local Dynamics of Two Peptide Dendrimers with the Same Backbone but with Different Side Groups in Their Spacers

In this paper, we perform computer simulation of two lysine-based dendrimers with Lys-2Lys and Lys-2Gly repeating units. These dendrimers were recently studied experimentally by NMR (Sci. Reports, 2018, 8, 8916) and tested as carriers for gene delivery (Bioorg. Chem., 2020, 95, 103504). Simulation w...

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Bibliographic Details
Main Authors: Sofia E. Mikhtaniuk, Valeriy V. Bezrodnyi, Oleg V. Shavykin, Igor M. Neelov, Nadezhda N. Sheveleva, Anastasia V. Penkova, Denis A. Markelov
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Polymers
Subjects:
Online Access:https://www.mdpi.com/2073-4360/12/8/1657