Ex Vivo Anti-Leukemic Effect of Exosome-like Grapefruit-Derived Nanovesicles from Organic Farming—The Potential Role of Ascorbic Acid

Ex Vivo Anti-Leukemic Effect of Exosome-like Grapefruit-Derived Nanovesicles from Organic Farming—The Potential Role of Ascorbic Acid

Citrus fruits are a natural source of ascorbic acid, and exosome-like nanovesicles obtained from these fruits contain measurable levels of ascorbic acid. We tested the ability of grapefruit-derived extracellular vesicles (EVs) to inhibit the growth of human leukemic cells and leukemic patient-derive...

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Bibliographic Details
Main Authors: Germana Castelli, Mariantonia Logozzi, Davide Mizzoni, Rossella Di Raimo, Annamaria Cerio, Vincenza Dolo, Luca Pasquini, Maria Screnci, Tiziana Ottone, Ugo Testa, Stefano Fais, Elvira Pelosi
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:International Journal of Molecular Sciences
Subjects:
grapefruit nanovesicles
ascorbic acid (vitamin C)
acute myeloid leukemia (AML)
oxidative stress
Online Access:https://www.mdpi.com/1422-0067/24/21/15663

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