Genome-wide screening for genes whose deletions confer sensitivity to mutagenic purine base analogs in yeast
<p>Abstract</p> <p>Background</p> <p><it>N</it>-hydroxylated base analogs, such as 6-hydroxylaminopurine (HAP) and 2-amino-6-hydroxylaminopurine (AHA), are strong mutagens in various organisms due to their ambiguous base-pairing properties. The systems prote...
Hauptverfasser: | Kozmin Stanislav G, Stepchenkova Elena I, Alenin Vladimir V, Pavlov Youri I |
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Format: | Artikel |
Sprache: | English |
Veröffentlicht: |
BMC
2005-06-01
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Schriftenreihe: | BMC Genetics |
Online Zugang: | http://www.biomedcentral.com/1471-2156/6/31 |
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