TAZ is required for chondrogenesis and skeletal development
Abstract Chondrogenesis is a major contributor to skeletal development and maintenance, as well as bone repair. Transcriptional coactivator with PDZ-binding motif (TAZ) is a key regulator of osteogenesis and adipogenesis, but how TAZ regulates chondrogenesis and skeletal development remains undefine...
Main Authors: | Yang Li, Shuting Yang, Ling Qin, Shuying Yang |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-04-01
|
Series: | Cell Discovery |
Online Access: | https://doi.org/10.1038/s41421-021-00254-5 |
Similar Items
-
Trp53 controls chondrogenesis and endochondral ossification by negative regulation of TAZ activity and stability via β-TrCP-mediated ubiquitination
by: Yang Li, et al.
Published: (2022-07-01) -
Type II collagen-positive progenitors are important stem cells in controlling skeletal development and vascular formation
by: Xinhua Li, et al.
Published: (2022-06-01) -
Hippo Signaling Mediators Yap and Taz Are Required in the Epicardium for Coronary Vasculature Development
by: Anamika Singh, et al.
Published: (2016-05-01) -
Mediated nuclear import and export of TAZ and the underlying molecular requirements
by: Michael Kofler, et al.
Published: (2018-11-01) -
YAP/TAZ Are Required to Suppress Osteogenic Differentiation of Vascular Smooth Muscle Cells
by: Lei Wang, et al.
Published: (2020-12-01)