Antenatal Toxoplasma gondii, Rubella and Cytomegalovirus Infection Screening Among Pregnant Women Attending Tertiary University Hospital

Objective: The present study was designed to determine the seroprevalance of Toxoplasma gondii, Rubella, and cytomegalovirus, to investigate the frequency of low and high avidity results among pregnant women and to contribute to the data of our country with the results obtained. Study Design: In th...

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Main Authors: Beril Gurlek, Sabri Colak
Format: Article
Language:English
Published: Medical Network 2019-08-01
Series:Gynecology Obstetrics & Reproductive Medicine
Subjects:
Online Access:http://gorm.com.tr/index.php/GORM/article/view/903
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author Beril Gurlek
Sabri Colak
author_facet Beril Gurlek
Sabri Colak
author_sort Beril Gurlek
collection DOAJ
description Objective: The present study was designed to determine the seroprevalance of Toxoplasma gondii, Rubella, and cytomegalovirus, to investigate the frequency of low and high avidity results among pregnant women and to contribute to the data of our country with the results obtained. Study Design: In the present study, the hospital records of the women who applied to the antenatal outpatient of the Rize Recep Tayyip Erdoğan University Medical Faculty during the first trimester between January 2016 and October 2018 were retrospectively reviewed. Toxoplasma gondii, RRubella and cytomegalovirus IgM, IgG and IgG avidity results were evaluated. Result: IgM positivity was found to be 0.83% (29/3490) for Toxoplasma gondii, 0.92% (32/3459) for Rubella and 1.90% (65/3404) for cytomegalovirus; IgG positivity was found to be 33.64% (1174/3490) for Toxoplasma gondii, 90.70% for Rubella (3140/3459), and 99.17% (3376/3404) for cytomegalovirus. Avidity of Toxoplasma gondii was found to be low (3.70%) in 1 patient, borderline (11.11%) in 3 patients, and high avidity in 23 patients (85.18%). Avidity of cytomegalovirus was found to be low (1.75%) in 1 patient, borderline (3.50%) in 2 patients and high avidity (94.73%) in 54 patients. Avidity of Rubella was found to be low (4%) in 1 patient, and high avidity (96%) was found in 24 patients. Conclusions: In our study, although the prevalence of acute infection with Rubella, cytomegalovirus and Toxoplasma gondii was shown to be low in pregnancy in Rize province, serological screening tests for monitoring and informing high-risk groups that are particularly seronegative appear to be important.
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spelling doaj.art-01b6b8563d224e79ab49da24ad65ff5f2023-02-15T16:18:22ZengMedical NetworkGynecology Obstetrics & Reproductive Medicine1300-47512019-08-01252748010.21613/GORM.2019.903679Antenatal Toxoplasma gondii, Rubella and Cytomegalovirus Infection Screening Among Pregnant Women Attending Tertiary University HospitalBeril Gurlek0Sabri Colak1Recep Tayyip Erdoğan ÜniversitesiRecep Tayyip Erdoğan ÜniversitesiObjective: The present study was designed to determine the seroprevalance of Toxoplasma gondii, Rubella, and cytomegalovirus, to investigate the frequency of low and high avidity results among pregnant women and to contribute to the data of our country with the results obtained. Study Design: In the present study, the hospital records of the women who applied to the antenatal outpatient of the Rize Recep Tayyip Erdoğan University Medical Faculty during the first trimester between January 2016 and October 2018 were retrospectively reviewed. Toxoplasma gondii, RRubella and cytomegalovirus IgM, IgG and IgG avidity results were evaluated. Result: IgM positivity was found to be 0.83% (29/3490) for Toxoplasma gondii, 0.92% (32/3459) for Rubella and 1.90% (65/3404) for cytomegalovirus; IgG positivity was found to be 33.64% (1174/3490) for Toxoplasma gondii, 90.70% for Rubella (3140/3459), and 99.17% (3376/3404) for cytomegalovirus. Avidity of Toxoplasma gondii was found to be low (3.70%) in 1 patient, borderline (11.11%) in 3 patients, and high avidity in 23 patients (85.18%). Avidity of cytomegalovirus was found to be low (1.75%) in 1 patient, borderline (3.50%) in 2 patients and high avidity (94.73%) in 54 patients. Avidity of Rubella was found to be low (4%) in 1 patient, and high avidity (96%) was found in 24 patients. Conclusions: In our study, although the prevalence of acute infection with Rubella, cytomegalovirus and Toxoplasma gondii was shown to be low in pregnancy in Rize province, serological screening tests for monitoring and informing high-risk groups that are particularly seronegative appear to be important.http://gorm.com.tr/index.php/GORM/article/view/903cytomegalovirüs, pegnancy, rubella, seroprevalance, toxoplasma
spellingShingle Beril Gurlek
Sabri Colak
Antenatal Toxoplasma gondii, Rubella and Cytomegalovirus Infection Screening Among Pregnant Women Attending Tertiary University Hospital
Gynecology Obstetrics & Reproductive Medicine
cytomegalovirüs, pegnancy, rubella, seroprevalance, toxoplasma
title Antenatal Toxoplasma gondii, Rubella and Cytomegalovirus Infection Screening Among Pregnant Women Attending Tertiary University Hospital
title_full Antenatal Toxoplasma gondii, Rubella and Cytomegalovirus Infection Screening Among Pregnant Women Attending Tertiary University Hospital
title_fullStr Antenatal Toxoplasma gondii, Rubella and Cytomegalovirus Infection Screening Among Pregnant Women Attending Tertiary University Hospital
title_full_unstemmed Antenatal Toxoplasma gondii, Rubella and Cytomegalovirus Infection Screening Among Pregnant Women Attending Tertiary University Hospital
title_short Antenatal Toxoplasma gondii, Rubella and Cytomegalovirus Infection Screening Among Pregnant Women Attending Tertiary University Hospital
title_sort antenatal toxoplasma gondii rubella and cytomegalovirus infection screening among pregnant women attending tertiary university hospital
topic cytomegalovirüs, pegnancy, rubella, seroprevalance, toxoplasma
url http://gorm.com.tr/index.php/GORM/article/view/903
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AT sabricolak antenataltoxoplasmagondiirubellaandcytomegalovirusinfectionscreeningamongpregnantwomenattendingtertiaryuniversityhospital