Clinical analysis of low flow bypass in the treatment of chronic symptomatic middle cerebral artery occlusion
Objective To investigate the efficacy and safety of low flow bypass in the treatment of chronic symptomatic middle cerebral artery occlusion (MCAO). Methods A total of 28 patients with chronic symptomatic MCAO who were treated in Tianjin Huanhu Hospital from January 2016 to December 2019 underwent s...
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| Format: | Article |
| Language: | English |
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Tianjin Huanhu Hospital
2021-07-01
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| Series: | Chinese Journal of Contemporary Neurology and Neurosurgery |
| Subjects: | |
| Online Access: | http://www.cjcnn.org/index.php/cjcnn/article/view/2360 |
| _version_ | 1818640356962467840 |
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| author | SUN Yang WANG Ben⁃lin LI Qi TONG Xiao⁃guang |
| author_facet | SUN Yang WANG Ben⁃lin LI Qi TONG Xiao⁃guang |
| author_sort | SUN Yang |
| collection | DOAJ |
| description | Objective To investigate the efficacy and safety of low flow bypass in the treatment of chronic symptomatic middle cerebral artery occlusion (MCAO). Methods A total of 28 patients with chronic symptomatic MCAO who were treated in Tianjin Huanhu Hospital from January 2016 to December 2019 underwent superficial temporal artery⁃middle cerebral artery (STA⁃MCA) bypass, and the prognosis of neurological function was assessed by modified Rankin Scale (mRS). DSA or CTA were reexamined to evaluate the patency of the anastomotic site of the bridging vessels, and PWI was reexamined to evaluate improvement of cerebral perfusion. Results All 28 patients underwent STA⁃MCA bypass successfully, the success rate of operation was 100%, and the patency rate of bridge vessels was 100%. The postoperative neurological function was improved compared with that before operation, and the difference was statistically significant (mRS score 1.43 ± 0.57 vs. 2.14 ± 0.36; t = 6.301, P = 0.000). Twelve months after operation, the cerebral blood flow (CBF) and cerebral blood volume (CBV) of the affected side were significantly increased, and the mean transit time (MTT) and time to peak (TTP) were significantly decreased compared with those before operation. The mean postoperative follow⁃up was (39.41 ± 9.39) months. No new ischemic events occurred, and the bridge vessels were patchy. Conclusions Low flow bypass is safe and effective in the treatment of chronic symptomatic MCAO. |
| first_indexed | 2024-12-16T23:09:59Z |
| format | Article |
| id | doaj.art-01b979e17c9e41b7902f98a0dfb26606 |
| institution | Directory Open Access Journal |
| issn | 1672-6731 1672-6731 |
| language | English |
| last_indexed | 2024-12-16T23:09:59Z |
| publishDate | 2021-07-01 |
| publisher | Tianjin Huanhu Hospital |
| record_format | Article |
| series | Chinese Journal of Contemporary Neurology and Neurosurgery |
| spelling | doaj.art-01b979e17c9e41b7902f98a0dfb266062022-12-21T22:12:26ZengTianjin Huanhu HospitalChinese Journal of Contemporary Neurology and Neurosurgery1672-67311672-67312021-07-01210754755210.3969/j.issn.1672⁃6731.2021.07.004Clinical analysis of low flow bypass in the treatment of chronic symptomatic middle cerebral artery occlusionSUN Yang0 WANG Ben⁃lin 1 LI Qi2TONG Xiao⁃guang 3 Grade 2019, Clinical College of Neurology, Neurosurgery and Neurorehabilitation, Tianjin Medical University, Tianjin 300070, ChinaGrade 2019, School of Medicine, Nankai University, Tianjin 300071, China Grade 2019, School of Medicine, Nankai University, Tianjin 300071, ChinaDepartment of Neurosurgery, Tianjin Huanhu Hospital, Tianjin 300350, ChinaObjective To investigate the efficacy and safety of low flow bypass in the treatment of chronic symptomatic middle cerebral artery occlusion (MCAO). Methods A total of 28 patients with chronic symptomatic MCAO who were treated in Tianjin Huanhu Hospital from January 2016 to December 2019 underwent superficial temporal artery⁃middle cerebral artery (STA⁃MCA) bypass, and the prognosis of neurological function was assessed by modified Rankin Scale (mRS). DSA or CTA were reexamined to evaluate the patency of the anastomotic site of the bridging vessels, and PWI was reexamined to evaluate improvement of cerebral perfusion. Results All 28 patients underwent STA⁃MCA bypass successfully, the success rate of operation was 100%, and the patency rate of bridge vessels was 100%. The postoperative neurological function was improved compared with that before operation, and the difference was statistically significant (mRS score 1.43 ± 0.57 vs. 2.14 ± 0.36; t = 6.301, P = 0.000). Twelve months after operation, the cerebral blood flow (CBF) and cerebral blood volume (CBV) of the affected side were significantly increased, and the mean transit time (MTT) and time to peak (TTP) were significantly decreased compared with those before operation. The mean postoperative follow⁃up was (39.41 ± 9.39) months. No new ischemic events occurred, and the bridge vessels were patchy. Conclusions Low flow bypass is safe and effective in the treatment of chronic symptomatic MCAO.http://www.cjcnn.org/index.php/cjcnn/article/view/2360arterial occlusive diseasesmiddle cerebral arterycerebral revascularizationtemporal arteriescerebral angiography |
| spellingShingle | SUN Yang WANG Ben⁃lin LI Qi TONG Xiao⁃guang Clinical analysis of low flow bypass in the treatment of chronic symptomatic middle cerebral artery occlusion Chinese Journal of Contemporary Neurology and Neurosurgery arterial occlusive diseases middle cerebral artery cerebral revascularization temporal arteries cerebral angiography |
| title | Clinical analysis of low flow bypass in the treatment of chronic symptomatic middle cerebral artery occlusion |
| title_full | Clinical analysis of low flow bypass in the treatment of chronic symptomatic middle cerebral artery occlusion |
| title_fullStr | Clinical analysis of low flow bypass in the treatment of chronic symptomatic middle cerebral artery occlusion |
| title_full_unstemmed | Clinical analysis of low flow bypass in the treatment of chronic symptomatic middle cerebral artery occlusion |
| title_short | Clinical analysis of low flow bypass in the treatment of chronic symptomatic middle cerebral artery occlusion |
| title_sort | clinical analysis of low flow bypass in the treatment of chronic symptomatic middle cerebral artery occlusion |
| topic | arterial occlusive diseases middle cerebral artery cerebral revascularization temporal arteries cerebral angiography |
| url | http://www.cjcnn.org/index.php/cjcnn/article/view/2360 |
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