| Summary: | The sensitivity of strains of microorganisms isolated from bioptates of atherosclerotic plaques to different antimicrobials was studied. For this study, the samples of atherosclerotic plaques from a group of patients that underwent elective carotid endarterectomy were used. Among 137 strains of coagulase-negative staphylococci 13.1 % of all isolates were methicillin-resistant, but all were sensitive to vancomycin, linezolid and moxifloxacin. Some strains of staphylococci possessed the resistance to erythromycin and tetracycline (16.3 %) and (13.9 %) respectively. The greatest resistance among coagulase-negative staphylococci to chloramphenicol (43.4 %) were identified. The high sensitivity of such bacteria to clindamycin, ciprofloxacin and gentamycin (92.6, 92.0 and 90.5 % respectively) were established. Among 197 isolates of Propionibacterium acnes all strains were highly sensitive to all antibiotics (amoxicillin, amoxicillin-clavulanic acid, benzylpenicillin, imipenem, clindamycin, piperacyllin, piperacyllin/tazobactam, ticarcillin, ticarcillin-clavulanic acid, chloramphenicol amd cefoxitin) which were tested. As exception was a metronidazole resistance to which bacteria are naturally refractory. The data obtained confirm that only small part of coagulase-negative staphylococci possessed the resistance to methicillin (13.1 %), but many among them demonstrated a high level of resistance to chloramphenicol. Between the strains of propionibacteria the acquired resistance to different antibacterials was not revealed.
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