Analysis of human brain tissue derived from DBS surgery

Analysis of human brain tissue derived from DBS surgery

Abstract Background Transcriptomic and proteomic profiling of human brain tissue is hindered by the availability of fresh samples from living patients. Postmortem samples usually represent the advanced disease stage of the patient. Furthermore, the postmortem interval can affect the transcriptomic a...

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Bibliographic Details
Main Authors: Salla M. Kangas, Jaakko Teppo, Maija J. Lahtinen, Anu Suoranta, Bishwa Ghimire, Pirkko Mattila, Johanna Uusimaa, Markku Varjosalo, Jani Katisko, Reetta Hinttala
Format: Article
Language:English
Published: BMC 2022-04-01
Series:Translational Neurodegeneration
Subjects:
Deep brain stimulation
Movement disorders
Brain
Proteomics
Transcriptomics
RNA sequencing
Online Access:https://doi.org/10.1186/s40035-022-00297-y

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