Analysis of Mortality in Unvaccinated Patients with COVID-19 and Cardiovascular Risk
COVID-19 is a contagious disease that has spread globally, killing millions of people around the world. In order to reduce the likelihood of in-hospital death due to COVID-19, it is reasonable to select a group of patients with a low probability of survival and to implement measures in advance to mi...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-08-01
|
| Series: | Journal of Clinical Medicine |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2077-0383/11/17/5004 |
| _version_ | 1797494832790241280 |
|---|---|
| author | Kathie Sarzyńska Filip Świątkowski Jarosław Janc Jan Zabierowski Beata Jankowska-Polańska Mariusz Chabowski |
| author_facet | Kathie Sarzyńska Filip Świątkowski Jarosław Janc Jan Zabierowski Beata Jankowska-Polańska Mariusz Chabowski |
| author_sort | Kathie Sarzyńska |
| collection | DOAJ |
| description | COVID-19 is a contagious disease that has spread globally, killing millions of people around the world. In order to reduce the likelihood of in-hospital death due to COVID-19, it is reasonable to select a group of patients with a low probability of survival and to implement measures in advance to minimize the risk of death. One way to do this is to establish cut-off values for the most commonly performed blood laboratory tests, above or below which the likelihood of death increases significantly. The aim of the study was to determine the basic laboratory parameters among unvaccinated patients hospitalized for COVID-19 with concomitant cardiovascular disease, which are the predictors of in-hospital death. Out of 1234 patients, 446 people who met the specific inclusion criteria were enrolled in the study. The multivariate regression analysis has shown that the independent predictors of death are: troponin levels of at least 0.033 μg/L (OR = 2.04 [1.10; 3.79]), creatinine of at least 1.88 mg/dL (OR = 2.88 [1.57; 5.30]), D-dimers of at least 0.97 g/L (OR = 2.04 [1.02; 4.07]), and C-reactive protein minimum of 0.89 mg/L (OR = 2.28 [1.24; 4.18]). |
| first_indexed | 2024-03-10T01:39:58Z |
| format | Article |
| id | doaj.art-01c65cab991f40cbadedc690fe5ca6b6 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-10T01:39:58Z |
| publishDate | 2022-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-01c65cab991f40cbadedc690fe5ca6b62023-11-23T13:25:59ZengMDPI AGJournal of Clinical Medicine2077-03832022-08-011117500410.3390/jcm11175004Analysis of Mortality in Unvaccinated Patients with COVID-19 and Cardiovascular RiskKathie Sarzyńska0Filip Świątkowski1Jarosław Janc2Jan Zabierowski3Beata Jankowska-Polańska4Mariusz Chabowski5Department of Nursing and Obstetrics, Faculty of Health Science, Wroclaw Medical University, 5 Bartla Street, 51-618 Wroclaw, PolandDepartment of Surgery, 4th Military Teaching Hospital, 50-981 Wroclaw, PolandDepartment of Anesthesiology and Intensive Therapy, 4th Military Teaching Hospital, 50-981 Wroclaw, PolandStudent Research Club No 180, Faculty of Medicine, Wroclaw Medical University, 50-556 Wroclaw, PolandResearch and Innovation Center, 4th Military Teaching Hospital, 50-981 Wroclaw, PolandDepartment of Surgery, 4th Military Teaching Hospital, 50-981 Wroclaw, PolandCOVID-19 is a contagious disease that has spread globally, killing millions of people around the world. In order to reduce the likelihood of in-hospital death due to COVID-19, it is reasonable to select a group of patients with a low probability of survival and to implement measures in advance to minimize the risk of death. One way to do this is to establish cut-off values for the most commonly performed blood laboratory tests, above or below which the likelihood of death increases significantly. The aim of the study was to determine the basic laboratory parameters among unvaccinated patients hospitalized for COVID-19 with concomitant cardiovascular disease, which are the predictors of in-hospital death. Out of 1234 patients, 446 people who met the specific inclusion criteria were enrolled in the study. The multivariate regression analysis has shown that the independent predictors of death are: troponin levels of at least 0.033 μg/L (OR = 2.04 [1.10; 3.79]), creatinine of at least 1.88 mg/dL (OR = 2.88 [1.57; 5.30]), D-dimers of at least 0.97 g/L (OR = 2.04 [1.02; 4.07]), and C-reactive protein minimum of 0.89 mg/L (OR = 2.28 [1.24; 4.18]).https://www.mdpi.com/2077-0383/11/17/5004COVID-19cardiovascular risklaboratory testmortality |
| spellingShingle | Kathie Sarzyńska Filip Świątkowski Jarosław Janc Jan Zabierowski Beata Jankowska-Polańska Mariusz Chabowski Analysis of Mortality in Unvaccinated Patients with COVID-19 and Cardiovascular Risk Journal of Clinical Medicine COVID-19 cardiovascular risk laboratory test mortality |
| title | Analysis of Mortality in Unvaccinated Patients with COVID-19 and Cardiovascular Risk |
| title_full | Analysis of Mortality in Unvaccinated Patients with COVID-19 and Cardiovascular Risk |
| title_fullStr | Analysis of Mortality in Unvaccinated Patients with COVID-19 and Cardiovascular Risk |
| title_full_unstemmed | Analysis of Mortality in Unvaccinated Patients with COVID-19 and Cardiovascular Risk |
| title_short | Analysis of Mortality in Unvaccinated Patients with COVID-19 and Cardiovascular Risk |
| title_sort | analysis of mortality in unvaccinated patients with covid 19 and cardiovascular risk |
| topic | COVID-19 cardiovascular risk laboratory test mortality |
| url | https://www.mdpi.com/2077-0383/11/17/5004 |
| work_keys_str_mv | AT kathiesarzynska analysisofmortalityinunvaccinatedpatientswithcovid19andcardiovascularrisk AT filipswiatkowski analysisofmortalityinunvaccinatedpatientswithcovid19andcardiovascularrisk AT jarosławjanc analysisofmortalityinunvaccinatedpatientswithcovid19andcardiovascularrisk AT janzabierowski analysisofmortalityinunvaccinatedpatientswithcovid19andcardiovascularrisk AT beatajankowskapolanska analysisofmortalityinunvaccinatedpatientswithcovid19andcardiovascularrisk AT mariuszchabowski analysisofmortalityinunvaccinatedpatientswithcovid19andcardiovascularrisk |