Morphogenesis, Growth Cycle and Molecular Regulation of Hair Follicles
As one of the main appendages of skin, hair follicles play an important role in the process of skin regeneration. Hair follicle is a tiny organ formed by the interaction between epidermis and dermis, which has complex and fine structure and periodic growth characteristics. The hair growth cycle is d...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-05-01
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| Series: | Frontiers in Cell and Developmental Biology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fcell.2022.899095/full |
| _version_ | 1818200904686370816 |
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| author | Xiangyu Lin Liang Zhu Jing He |
| author_facet | Xiangyu Lin Liang Zhu Jing He |
| author_sort | Xiangyu Lin |
| collection | DOAJ |
| description | As one of the main appendages of skin, hair follicles play an important role in the process of skin regeneration. Hair follicle is a tiny organ formed by the interaction between epidermis and dermis, which has complex and fine structure and periodic growth characteristics. The hair growth cycle is divided into three continuous stages, growth (anagen), apoptosis-driven regression (catagen) and relative quiescence (telogen). And The Morphogenesis and cycle of hair follicles are regulated by a variety of signal pathways. When the signal molecules in the pathways are abnormal, it will affect the development and cycle of hair follicles, which will lead to hair follicle-related diseases.This article will review the structure, development, cycle and molecular regulation of hair follicles, in order to provide new ideas for solving diseases and forming functional hair follicle. |
| first_indexed | 2024-12-12T02:45:04Z |
| format | Article |
| id | doaj.art-01cac4b2ce6f4fec8a28da9bbd793583 |
| institution | Directory Open Access Journal |
| issn | 2296-634X |
| language | English |
| last_indexed | 2024-12-12T02:45:04Z |
| publishDate | 2022-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cell and Developmental Biology |
| spelling | doaj.art-01cac4b2ce6f4fec8a28da9bbd7935832022-12-22T00:41:03ZengFrontiers Media S.A.Frontiers in Cell and Developmental Biology2296-634X2022-05-011010.3389/fcell.2022.899095899095Morphogenesis, Growth Cycle and Molecular Regulation of Hair FolliclesXiangyu LinLiang ZhuJing HeAs one of the main appendages of skin, hair follicles play an important role in the process of skin regeneration. Hair follicle is a tiny organ formed by the interaction between epidermis and dermis, which has complex and fine structure and periodic growth characteristics. The hair growth cycle is divided into three continuous stages, growth (anagen), apoptosis-driven regression (catagen) and relative quiescence (telogen). And The Morphogenesis and cycle of hair follicles are regulated by a variety of signal pathways. When the signal molecules in the pathways are abnormal, it will affect the development and cycle of hair follicles, which will lead to hair follicle-related diseases.This article will review the structure, development, cycle and molecular regulation of hair follicles, in order to provide new ideas for solving diseases and forming functional hair follicle.https://www.frontiersin.org/articles/10.3389/fcell.2022.899095/fullhair folliclesmorphogenesishair cyclingWNTBMP |
| spellingShingle | Xiangyu Lin Liang Zhu Jing He Morphogenesis, Growth Cycle and Molecular Regulation of Hair Follicles Frontiers in Cell and Developmental Biology hair follicles morphogenesis hair cycling WNT BMP |
| title | Morphogenesis, Growth Cycle and Molecular Regulation of Hair Follicles |
| title_full | Morphogenesis, Growth Cycle and Molecular Regulation of Hair Follicles |
| title_fullStr | Morphogenesis, Growth Cycle and Molecular Regulation of Hair Follicles |
| title_full_unstemmed | Morphogenesis, Growth Cycle and Molecular Regulation of Hair Follicles |
| title_short | Morphogenesis, Growth Cycle and Molecular Regulation of Hair Follicles |
| title_sort | morphogenesis growth cycle and molecular regulation of hair follicles |
| topic | hair follicles morphogenesis hair cycling WNT BMP |
| url | https://www.frontiersin.org/articles/10.3389/fcell.2022.899095/full |
| work_keys_str_mv | AT xiangyulin morphogenesisgrowthcycleandmolecularregulationofhairfollicles AT liangzhu morphogenesisgrowthcycleandmolecularregulationofhairfollicles AT jinghe morphogenesisgrowthcycleandmolecularregulationofhairfollicles |