A SIMIND Monte Carlo Simulation Study on CdTe and NaI (Tl) Thickness as Detectors of a Small Animal SPECT System
Purpose: Micro-SPECT system has recently been introduced on nuclear medicine in the preclinical and research in which NaI (Tl) and Cadmium Telluride (CdTe) are used as the gamma-ray detectors with more generally use of NaI (Tl). The present study aimed to evaluate different thicknesses of the NaI (...
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2022-07-01
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| Series: | Frontiers in Biomedical Technologies |
| Subjects: | |
| Online Access: | https://fbt.tums.ac.ir/index.php/fbt/article/view/377 |
| _version_ | 1811271940596301824 |
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| author | Samira Abbaspour Babak Mahmoudian Seyed Rasoul Zakavi Jalil Pirayesh Islamian |
| author_facet | Samira Abbaspour Babak Mahmoudian Seyed Rasoul Zakavi Jalil Pirayesh Islamian |
| author_sort | Samira Abbaspour |
| collection | DOAJ |
| description |
Purpose: Micro-SPECT system has recently been introduced on nuclear medicine in the preclinical and research in which NaI (Tl) and Cadmium Telluride (CdTe) are used as the gamma-ray detectors with more generally use of NaI (Tl). The present study aimed to evaluate different thicknesses of the NaI (Tl) and (CdTe) detectors on functional parameters of a micro-SPECT system.
Materials and Methods: A Micro-SPECT system with CdTe semiconductor detector and a hexagonal parallel hole collimator with a hole diameter of 0.11 mm, high of 24.05 mm, and septal thickness of 0.016 mm was simulated by SIMIND Monte Carlo program. The system performance was assessed by comparing the functional parameters, including system efficiency, sensitivity, energy and spatial resolution with the NaI (Tl) detector. The simulated scans of a 99mTc point source, a digital micro-Jacszack phantom, and a voxelized MOBY mouse phantom with the system were prepared to evaluate image quality.
Results: The functional parameters; sensitivity, efficiency, planar spatial resolution, and image contrast of CdTe detector were determined 1.4, 1.2, 1.7, and 1.8 times higher than those of NaI (Tl), respectively. Moreover, the calculated energy resolution of CdTe and NaI (Tl) detectors was obtained 6.2% and 10.2% at 141 KeV, respectively. In the filtered back projection (FBP) reconstructed images of the micro-Jacszack phantom, minimum detectable size of the cold rods with CdTe and NaI (Tl) detectors were obtained 0.79 mm and 0.95 mm, respectively.
Conclusion: The imaging system with a 5.5 mm thickness CdTe detector provided better image quality and showed considerable efficiency.
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| first_indexed | 2024-04-12T22:30:09Z |
| format | Article |
| id | doaj.art-01cfba39469b41f08f447194c6fd8f93 |
| institution | Directory Open Access Journal |
| issn | 2345-5837 |
| language | English |
| last_indexed | 2024-04-12T22:30:09Z |
| publishDate | 2022-07-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Frontiers in Biomedical Technologies |
| spelling | doaj.art-01cfba39469b41f08f447194c6fd8f932022-12-22T03:13:59ZengTehran University of Medical SciencesFrontiers in Biomedical Technologies2345-58372022-07-019410.18502/fbt.v9i4.10424A SIMIND Monte Carlo Simulation Study on CdTe and NaI (Tl) Thickness as Detectors of a Small Animal SPECT SystemSamira Abbaspour0Babak Mahmoudian1Seyed Rasoul Zakavi2Jalil Pirayesh Islamian3Department of Medical Physics, School of Medicine, Tehran University of Medical Sciences, Tehran, IranDepartment of Nuclear Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, IranNuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, IranDepartment of Medical Physics, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran Purpose: Micro-SPECT system has recently been introduced on nuclear medicine in the preclinical and research in which NaI (Tl) and Cadmium Telluride (CdTe) are used as the gamma-ray detectors with more generally use of NaI (Tl). The present study aimed to evaluate different thicknesses of the NaI (Tl) and (CdTe) detectors on functional parameters of a micro-SPECT system. Materials and Methods: A Micro-SPECT system with CdTe semiconductor detector and a hexagonal parallel hole collimator with a hole diameter of 0.11 mm, high of 24.05 mm, and septal thickness of 0.016 mm was simulated by SIMIND Monte Carlo program. The system performance was assessed by comparing the functional parameters, including system efficiency, sensitivity, energy and spatial resolution with the NaI (Tl) detector. The simulated scans of a 99mTc point source, a digital micro-Jacszack phantom, and a voxelized MOBY mouse phantom with the system were prepared to evaluate image quality. Results: The functional parameters; sensitivity, efficiency, planar spatial resolution, and image contrast of CdTe detector were determined 1.4, 1.2, 1.7, and 1.8 times higher than those of NaI (Tl), respectively. Moreover, the calculated energy resolution of CdTe and NaI (Tl) detectors was obtained 6.2% and 10.2% at 141 KeV, respectively. In the filtered back projection (FBP) reconstructed images of the micro-Jacszack phantom, minimum detectable size of the cold rods with CdTe and NaI (Tl) detectors were obtained 0.79 mm and 0.95 mm, respectively. Conclusion: The imaging system with a 5.5 mm thickness CdTe detector provided better image quality and showed considerable efficiency. https://fbt.tums.ac.ir/index.php/fbt/article/view/377Cadmium TellurideResolutionImage QualityMicro Single Photon Emission Computed TomographySimulating Medical Imaging Nuclear Detectors Monte Carlo |
| spellingShingle | Samira Abbaspour Babak Mahmoudian Seyed Rasoul Zakavi Jalil Pirayesh Islamian A SIMIND Monte Carlo Simulation Study on CdTe and NaI (Tl) Thickness as Detectors of a Small Animal SPECT System Frontiers in Biomedical Technologies Cadmium Telluride Resolution Image Quality Micro Single Photon Emission Computed Tomography Simulating Medical Imaging Nuclear Detectors Monte Carlo |
| title | A SIMIND Monte Carlo Simulation Study on CdTe and NaI (Tl) Thickness as Detectors of a Small Animal SPECT System |
| title_full | A SIMIND Monte Carlo Simulation Study on CdTe and NaI (Tl) Thickness as Detectors of a Small Animal SPECT System |
| title_fullStr | A SIMIND Monte Carlo Simulation Study on CdTe and NaI (Tl) Thickness as Detectors of a Small Animal SPECT System |
| title_full_unstemmed | A SIMIND Monte Carlo Simulation Study on CdTe and NaI (Tl) Thickness as Detectors of a Small Animal SPECT System |
| title_short | A SIMIND Monte Carlo Simulation Study on CdTe and NaI (Tl) Thickness as Detectors of a Small Animal SPECT System |
| title_sort | simind monte carlo simulation study on cdte and nai tl thickness as detectors of a small animal spect system |
| topic | Cadmium Telluride Resolution Image Quality Micro Single Photon Emission Computed Tomography Simulating Medical Imaging Nuclear Detectors Monte Carlo |
| url | https://fbt.tums.ac.ir/index.php/fbt/article/view/377 |
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