Combined endophthalmitis and orbital cellulitis in patients with corona virus disease (COVID-19)

Abstract Purpose To document the presentation of unilateral combined endophthalmitis and orbital cellulitis in patients with COVID-19 infection and study their prognosis. Patients and methods This interventional case series study included 9 patients referred to the Ophthalmology Department, Minia Un...

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Main Authors: Mohamed Farouk Sayed Othman Abdelkader, Ahmed Mohamed Kamal Elshafei, Mahmoud Mamdouh Nassar, Mostafa A. Abu Elela, Raafat Mohyeldeen Abdelrahman Abdallah
Format: Article
Language:English
Published: SpringerOpen 2021-09-01
Series:Journal of Ophthalmic Inflammation and Infection
Subjects:
Online Access:https://doi.org/10.1186/s12348-021-00258-y
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author Mohamed Farouk Sayed Othman Abdelkader
Ahmed Mohamed Kamal Elshafei
Mahmoud Mamdouh Nassar
Mostafa A. Abu Elela
Raafat Mohyeldeen Abdelrahman Abdallah
author_facet Mohamed Farouk Sayed Othman Abdelkader
Ahmed Mohamed Kamal Elshafei
Mahmoud Mamdouh Nassar
Mostafa A. Abu Elela
Raafat Mohyeldeen Abdelrahman Abdallah
author_sort Mohamed Farouk Sayed Othman Abdelkader
collection DOAJ
description Abstract Purpose To document the presentation of unilateral combined endophthalmitis and orbital cellulitis in patients with COVID-19 infection and study their prognosis. Patients and methods This interventional case series study included 9 patients referred to the Ophthalmology Department, Minia University Hospital with unilateral combined endophthalmitis and orbital cellulitis between April 2020 and March 2021. In addition to the COVID-19 work-up, all patients were subjected to full ophthalmological evaluation and managed according to their ophthalmic and systemic disease. Results The patients were 5 females and 4 males. They had clinical, laboratory and imaging findings that confirmed COVID-19 infection. All patients had unilateral endophthalmitis with orbital cellulitis and profound visual loss in the affected eye. Three patients died due to respiratory failure, while 6 patients recovered systemically. The survived patients developed atrophia bulbi in 4 patients and in 2 patients, the globe retained normal size but with complete visual loss. Conclusion Combined endophthalmitis and orbital cellulitis can be one of the early presentations of patients with COVID-19 infection with poor visual prognosis. Trial registration Clinical registration: clinicaltrials.gov identifier: NCT04456556 .
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spelling doaj.art-01d241bff71346309412f6f1ec0e2fe92022-12-21T18:51:39ZengSpringerOpenJournal of Ophthalmic Inflammation and Infection1869-57602021-09-011111610.1186/s12348-021-00258-yCombined endophthalmitis and orbital cellulitis in patients with corona virus disease (COVID-19)Mohamed Farouk Sayed Othman Abdelkader0Ahmed Mohamed Kamal Elshafei1Mahmoud Mamdouh Nassar2Mostafa A. Abu Elela3Raafat Mohyeldeen Abdelrahman Abdallah4Ophthalmology Department, Faculty of Medicine, Minia UniversityOphthalmology Department, Faculty of Medicine, Minia UniversityOphthalmology Department, Faculty of Medicine, Minia UniversityDepartment of Clinical pathology, Faculty of Medicine, Minia UniversityOphthalmology Department, Faculty of Medicine, Minia UniversityAbstract Purpose To document the presentation of unilateral combined endophthalmitis and orbital cellulitis in patients with COVID-19 infection and study their prognosis. Patients and methods This interventional case series study included 9 patients referred to the Ophthalmology Department, Minia University Hospital with unilateral combined endophthalmitis and orbital cellulitis between April 2020 and March 2021. In addition to the COVID-19 work-up, all patients were subjected to full ophthalmological evaluation and managed according to their ophthalmic and systemic disease. Results The patients were 5 females and 4 males. They had clinical, laboratory and imaging findings that confirmed COVID-19 infection. All patients had unilateral endophthalmitis with orbital cellulitis and profound visual loss in the affected eye. Three patients died due to respiratory failure, while 6 patients recovered systemically. The survived patients developed atrophia bulbi in 4 patients and in 2 patients, the globe retained normal size but with complete visual loss. Conclusion Combined endophthalmitis and orbital cellulitis can be one of the early presentations of patients with COVID-19 infection with poor visual prognosis. Trial registration Clinical registration: clinicaltrials.gov identifier: NCT04456556 .https://doi.org/10.1186/s12348-021-00258-yCOVID-19Orbital cellulitisEndophthalmitis
spellingShingle Mohamed Farouk Sayed Othman Abdelkader
Ahmed Mohamed Kamal Elshafei
Mahmoud Mamdouh Nassar
Mostafa A. Abu Elela
Raafat Mohyeldeen Abdelrahman Abdallah
Combined endophthalmitis and orbital cellulitis in patients with corona virus disease (COVID-19)
Journal of Ophthalmic Inflammation and Infection
COVID-19
Orbital cellulitis
Endophthalmitis
title Combined endophthalmitis and orbital cellulitis in patients with corona virus disease (COVID-19)
title_full Combined endophthalmitis and orbital cellulitis in patients with corona virus disease (COVID-19)
title_fullStr Combined endophthalmitis and orbital cellulitis in patients with corona virus disease (COVID-19)
title_full_unstemmed Combined endophthalmitis and orbital cellulitis in patients with corona virus disease (COVID-19)
title_short Combined endophthalmitis and orbital cellulitis in patients with corona virus disease (COVID-19)
title_sort combined endophthalmitis and orbital cellulitis in patients with corona virus disease covid 19
topic COVID-19
Orbital cellulitis
Endophthalmitis
url https://doi.org/10.1186/s12348-021-00258-y
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