Natural foods resources and dietary ingredients for the amelioration of Helicobacter pylori infection
Helicobacter pylori (H. pylori) is a gastric-persistent pathogen that can cause peptic ulcer disease, gastric cancer, and mucosal-associated lymphoid tissue lymphoma. This pathogen is commonly treated with antibiotic-based triple or quadruple therapy. However, antibiotic therapy could result in the...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-12-01
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| Series: | Frontiers in Medicine |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2023.1324473/full |
| _version_ | 1797403199486820352 |
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| author | Chengyuan Wang Meixiang Yao Hongguang Zhong Stephene S. Meena Fuxing Shu Shaoping Nie Mingyong Xie |
| author_facet | Chengyuan Wang Meixiang Yao Hongguang Zhong Stephene S. Meena Fuxing Shu Shaoping Nie Mingyong Xie |
| author_sort | Chengyuan Wang |
| collection | DOAJ |
| description | Helicobacter pylori (H. pylori) is a gastric-persistent pathogen that can cause peptic ulcer disease, gastric cancer, and mucosal-associated lymphoid tissue lymphoma. This pathogen is commonly treated with antibiotic-based triple or quadruple therapy. However, antibiotic therapy could result in the bacterial resistance, imbalance of gut microbiota, and damage to the liver and kidneys, etc. Therefore, there is an urgent need for alternative therapeutic strategies. Interestingly, natural food resources, like vegetables, fruits, spices, and edible herbs, have potent inhibitory effects on H. pylori. In this review, we systematically summarized these foods with supporting evidence from both animal and clinical studies. The results have indicated that natural foods may possess temporary inhibition effect on H. pylori rather than durable eradication, and may help to reduce H. pylori colonization, enhance the effect of antibiotics and modulate the host’s immune response. |
| first_indexed | 2024-03-09T02:35:03Z |
| format | Article |
| id | doaj.art-01d33ec23dd444c59a6c338b9a190bef |
| institution | Directory Open Access Journal |
| issn | 2296-858X |
| language | English |
| last_indexed | 2024-03-09T02:35:03Z |
| publishDate | 2023-12-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj.art-01d33ec23dd444c59a6c338b9a190bef2023-12-06T08:35:58ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2023-12-011010.3389/fmed.2023.13244731324473Natural foods resources and dietary ingredients for the amelioration of Helicobacter pylori infectionChengyuan Wang0Meixiang Yao1Hongguang Zhong2Stephene S. Meena3Fuxing Shu4Shaoping Nie5Mingyong Xie6State Key Laboratory of Food Science and Technology, China-Canada Joint Laboratory of Food Science and Technology (Nanchang), Key Laboratory of Bioactive Polysaccharides of Jiangxi Province, Nanchang University, Nanchang, Jiangxi, ChinaJiangzhong Dietary Therapy Technology Co. Ltd, Jiujiang, Jiangxi, ChinaJiangzhong Dietary Therapy Technology Co. Ltd, Jiujiang, Jiangxi, ChinaJiangzhong Cancer Research, Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, ChinaCollege of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, Jiangsu, ChinaState Key Laboratory of Food Science and Technology, China-Canada Joint Laboratory of Food Science and Technology (Nanchang), Key Laboratory of Bioactive Polysaccharides of Jiangxi Province, Nanchang University, Nanchang, Jiangxi, ChinaState Key Laboratory of Food Science and Technology, China-Canada Joint Laboratory of Food Science and Technology (Nanchang), Key Laboratory of Bioactive Polysaccharides of Jiangxi Province, Nanchang University, Nanchang, Jiangxi, ChinaHelicobacter pylori (H. pylori) is a gastric-persistent pathogen that can cause peptic ulcer disease, gastric cancer, and mucosal-associated lymphoid tissue lymphoma. This pathogen is commonly treated with antibiotic-based triple or quadruple therapy. However, antibiotic therapy could result in the bacterial resistance, imbalance of gut microbiota, and damage to the liver and kidneys, etc. Therefore, there is an urgent need for alternative therapeutic strategies. Interestingly, natural food resources, like vegetables, fruits, spices, and edible herbs, have potent inhibitory effects on H. pylori. In this review, we systematically summarized these foods with supporting evidence from both animal and clinical studies. The results have indicated that natural foods may possess temporary inhibition effect on H. pylori rather than durable eradication, and may help to reduce H. pylori colonization, enhance the effect of antibiotics and modulate the host’s immune response.https://www.frontiersin.org/articles/10.3389/fmed.2023.1324473/fullHelicobacter pyloriantibioticsnatural foodseradicationdietatary ingredients |
| spellingShingle | Chengyuan Wang Meixiang Yao Hongguang Zhong Stephene S. Meena Fuxing Shu Shaoping Nie Mingyong Xie Natural foods resources and dietary ingredients for the amelioration of Helicobacter pylori infection Frontiers in Medicine Helicobacter pylori antibiotics natural foods eradication dietatary ingredients |
| title | Natural foods resources and dietary ingredients for the amelioration of Helicobacter pylori infection |
| title_full | Natural foods resources and dietary ingredients for the amelioration of Helicobacter pylori infection |
| title_fullStr | Natural foods resources and dietary ingredients for the amelioration of Helicobacter pylori infection |
| title_full_unstemmed | Natural foods resources and dietary ingredients for the amelioration of Helicobacter pylori infection |
| title_short | Natural foods resources and dietary ingredients for the amelioration of Helicobacter pylori infection |
| title_sort | natural foods resources and dietary ingredients for the amelioration of helicobacter pylori infection |
| topic | Helicobacter pylori antibiotics natural foods eradication dietatary ingredients |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2023.1324473/full |
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