Diagnostic utility of rapid tests to detect IgG/IgM antibodies against COVID-19
<p><strong>Background</strong>: Rapid tests for the diagnosis of SARS-CoV-2 are attractive options due to their simplicity, speed and cost-effectiveness; but they have different degrees of sensitivity and diagnostic specificity.<br /><strong>Objective</strong>: to...
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| Format: | Article |
| Language: | Spanish |
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Centro Provincial de Información de Ciencias Médicas. Cienfuegos
2022-03-01
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| Series: | Medisur |
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| Online Access: | http://medisur.sld.cu/index.php/medisur/article/view/5230 |
| _version_ | 1797277683647774720 |
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| author | Pedro Sánchez Frenes Dayamí García Torres María de Jesús Sánchez Bouza Gippsy Mendoza Cartaya Mavis Portela Sánchez |
| author_facet | Pedro Sánchez Frenes Dayamí García Torres María de Jesús Sánchez Bouza Gippsy Mendoza Cartaya Mavis Portela Sánchez |
| author_sort | Pedro Sánchez Frenes |
| collection | DOAJ |
| description | <p><strong>Background</strong>: Rapid tests for the diagnosis of SARS-CoV-2 are attractive options due to their simplicity, speed and cost-effectiveness; but they have different degrees of sensitivity and diagnostic specificity.<br /><strong>Objective</strong>: to evaluate the analytical performance of rapid tests to detect IgG/IgM antibodies against COVID-19.<br /><strong>Methods</strong>: descriptive study, carried out with patients admitted to the Héroes de Playa Girón Specialized Ambulatory Center, in Cienfuegos, with a presumptive, probable or confirmed diagnosis of COVID-19 during two periods of time. All of them underwent a rapid test to detect anti-COVID-19 antibodies, in addition to a confirmatory molecular biology test. Diagnostic sensitivity and specificity, predictive values, and rapid test efficiency were calculated within a 95% confidence interval.<br /><strong>Results</strong>: excellent specificity (98.75%) and regular sensitivity (54.54%) were obtained, as well as good predictive values and overall diagnostic efficiency.<strong><br />Conclusion</strong>: The rapid anti-COVID-19 tests evaluated showed adequate diagnostic performance. They constitute an affordable and valuable diagnostic alternative to assess previous exposure to SARS-CoV-2. Its clinical use is restricted to certain medical situations; however, they constitute a useful epidemiological tool.</p> |
| first_indexed | 2024-03-07T15:52:52Z |
| format | Article |
| id | doaj.art-01d4d1e1862d4bf3a8eefe69e404c284 |
| institution | Directory Open Access Journal |
| issn | 1727-897X |
| language | Spanish |
| last_indexed | 2024-03-07T15:52:52Z |
| publishDate | 2022-03-01 |
| publisher | Centro Provincial de Información de Ciencias Médicas. Cienfuegos |
| record_format | Article |
| series | Medisur |
| spelling | doaj.art-01d4d1e1862d4bf3a8eefe69e404c2842024-03-04T23:09:53ZspaCentro Provincial de Información de Ciencias Médicas. CienfuegosMedisur1727-897X2022-03-012023743812110Diagnostic utility of rapid tests to detect IgG/IgM antibodies against COVID-19Pedro Sánchez Frenes0Dayamí García Torres1María de Jesús Sánchez Bouza2Gippsy Mendoza Cartaya3Mavis Portela Sánchez4Banco Provincial de Sangre. CienfuegosHospital Centro Especializado Ambulatorio Héroes de Playa Girón. CienfuegosUniversidad de Ciencias Médicas de Cienfuegos. CienfuegosCentro Provincial de Higiene, Epidemiología y Microbiología de Cienfuegos. CienfuegosHospital Centro Especializado Ambulatorio Héroes de Playa Girón. Cienfuegos<p><strong>Background</strong>: Rapid tests for the diagnosis of SARS-CoV-2 are attractive options due to their simplicity, speed and cost-effectiveness; but they have different degrees of sensitivity and diagnostic specificity.<br /><strong>Objective</strong>: to evaluate the analytical performance of rapid tests to detect IgG/IgM antibodies against COVID-19.<br /><strong>Methods</strong>: descriptive study, carried out with patients admitted to the Héroes de Playa Girón Specialized Ambulatory Center, in Cienfuegos, with a presumptive, probable or confirmed diagnosis of COVID-19 during two periods of time. All of them underwent a rapid test to detect anti-COVID-19 antibodies, in addition to a confirmatory molecular biology test. Diagnostic sensitivity and specificity, predictive values, and rapid test efficiency were calculated within a 95% confidence interval.<br /><strong>Results</strong>: excellent specificity (98.75%) and regular sensitivity (54.54%) were obtained, as well as good predictive values and overall diagnostic efficiency.<strong><br />Conclusion</strong>: The rapid anti-COVID-19 tests evaluated showed adequate diagnostic performance. They constitute an affordable and valuable diagnostic alternative to assess previous exposure to SARS-CoV-2. Its clinical use is restricted to certain medical situations; however, they constitute a useful epidemiological tool.</p>http://medisur.sld.cu/index.php/medisur/article/view/5230anticuerposinfección por coronavirustécnicas de laboratorio clínicopruebas serológicas |
| spellingShingle | Pedro Sánchez Frenes Dayamí García Torres María de Jesús Sánchez Bouza Gippsy Mendoza Cartaya Mavis Portela Sánchez Diagnostic utility of rapid tests to detect IgG/IgM antibodies against COVID-19 Medisur anticuerpos infección por coronavirus técnicas de laboratorio clínico pruebas serológicas |
| title | Diagnostic utility of rapid tests to detect IgG/IgM antibodies against COVID-19 |
| title_full | Diagnostic utility of rapid tests to detect IgG/IgM antibodies against COVID-19 |
| title_fullStr | Diagnostic utility of rapid tests to detect IgG/IgM antibodies against COVID-19 |
| title_full_unstemmed | Diagnostic utility of rapid tests to detect IgG/IgM antibodies against COVID-19 |
| title_short | Diagnostic utility of rapid tests to detect IgG/IgM antibodies against COVID-19 |
| title_sort | diagnostic utility of rapid tests to detect igg igm antibodies against covid 19 |
| topic | anticuerpos infección por coronavirus técnicas de laboratorio clínico pruebas serológicas |
| url | http://medisur.sld.cu/index.php/medisur/article/view/5230 |
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