Proteomic analysis of exosomes secreted during the epithelial-mesenchymal transition and potential biomarkers of mesenchymal high-grade serous ovarian carcinoma

Proteomic analysis of exosomes secreted during the epithelial-mesenchymal transition and potential biomarkers of mesenchymal high-grade serous ovarian carcinoma

Abstract Background The epithelial-mesenchymal transition (EMT) promotes cell signaling and morphology alterations, contributing to cancer progression. Exosomes, extracellular vesicles containing proteins involved in cell-cell communication, have emerged as a potential source of biomarkers for sever...

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Bibliographic Details
Main Authors: Germano Aguiar Ferreira, Carolina Hassibe Thomé, Clarice Izumi, Mariana Lopes Grassi, Guilherme Pauperio Lanfredi, Marcus Smolka, Vitor Marcel Faça, Francisco José Candido dos Reis
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Journal of Ovarian Research
Subjects:
Ovarian cancer
Epithelial-mesenchymal transition
Extracellular vesicles
Exosomes
Secretome
Online Access:https://doi.org/10.1186/s13048-023-01304-0

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