Performance of “VIKIA Malaria Ag Pf/Pan” (IMACCESS®), a new malaria rapid diagnostic test for detection of symptomatic malaria infections
<p>Abstract</p> <p>Background</p> <p>Recently, IMACCESS<b>®</b> developed a new malaria test (VIKIA Malaria Ag Pf/Pan™), based on the detection of falciparum malaria (HRP-2) and non-falciparum malaria (aldolase).</p> <p>Methods</p> <p>...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2012-08-01
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| Series: | Malaria Journal |
| Online Access: | http://www.malariajournal.com/content/11/1/295 |
| _version_ | 1811314440958640128 |
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| author | Chou Monidarin Kim Saorin Khim Nimol Chy Sophy Sum Sarorn Dourng Dany Canier Lydie Nguon Chea Ménard Didier |
| author_facet | Chou Monidarin Kim Saorin Khim Nimol Chy Sophy Sum Sarorn Dourng Dany Canier Lydie Nguon Chea Ménard Didier |
| author_sort | Chou Monidarin |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>Recently, IMACCESS<b>®</b> developed a new malaria test (VIKIA Malaria Ag Pf/Pan™), based on the detection of falciparum malaria (HRP-2) and non-falciparum malaria (aldolase).</p> <p>Methods</p> <p>The performance of this new malaria rapid diagnostic test (RDT) was assessed using 1,000 febrile patients seeking malaria treatment in four health centres in Cambodia from August to December 2011. The results of the VIKIA Malaria Ag Pf/Pan were compared with those obtained by microscopy, the CareStart Malaria™ RDT (AccessBio®) which is currently used in Cambodia, and real-time PCR (as “gold standard”).</p> <p>Results</p> <p>The best performances of the VIKIA Malaria Ag Pf/Pan™ test for detection of both <it>Plasmodium falciparum</it> and non-<it>P. falciparum</it> were with 20–30 min reading times (sensitivity of 93.4% for <it>P. falciparum</it> and 82.8% for non-<it>P. falciparum</it> and specificity of 98.6% for <it>P. falciparum</it> and 98.9% for non-<it>P. falciparum</it>) and were similar to those for the CareStart Malaria™ test.</p> <p>Conclusions</p> <p>This new RDT performs similarly well as other commercially available tests (especially the CareStart Malaria™ test, used as comparator), and conforms to the World Health Organization’s recommendations for RDT performance. It is a good alternative tool for the diagnosis of malaria in endemic areas.</p> |
| first_indexed | 2024-04-13T11:11:44Z |
| format | Article |
| id | doaj.art-01d7990e2b5c4a2e9253dfd5a6de3ac2 |
| institution | Directory Open Access Journal |
| issn | 1475-2875 |
| language | English |
| last_indexed | 2024-04-13T11:11:44Z |
| publishDate | 2012-08-01 |
| publisher | BMC |
| record_format | Article |
| series | Malaria Journal |
| spelling | doaj.art-01d7990e2b5c4a2e9253dfd5a6de3ac22022-12-22T02:49:05ZengBMCMalaria Journal1475-28752012-08-0111129510.1186/1475-2875-11-295Performance of “VIKIA Malaria Ag Pf/Pan” (IMACCESS®), a new malaria rapid diagnostic test for detection of symptomatic malaria infectionsChou MonidarinKim SaorinKhim NimolChy SophySum SarornDourng DanyCanier LydieNguon CheaMénard Didier<p>Abstract</p> <p>Background</p> <p>Recently, IMACCESS<b>®</b> developed a new malaria test (VIKIA Malaria Ag Pf/Pan™), based on the detection of falciparum malaria (HRP-2) and non-falciparum malaria (aldolase).</p> <p>Methods</p> <p>The performance of this new malaria rapid diagnostic test (RDT) was assessed using 1,000 febrile patients seeking malaria treatment in four health centres in Cambodia from August to December 2011. The results of the VIKIA Malaria Ag Pf/Pan were compared with those obtained by microscopy, the CareStart Malaria™ RDT (AccessBio®) which is currently used in Cambodia, and real-time PCR (as “gold standard”).</p> <p>Results</p> <p>The best performances of the VIKIA Malaria Ag Pf/Pan™ test for detection of both <it>Plasmodium falciparum</it> and non-<it>P. falciparum</it> were with 20–30 min reading times (sensitivity of 93.4% for <it>P. falciparum</it> and 82.8% for non-<it>P. falciparum</it> and specificity of 98.6% for <it>P. falciparum</it> and 98.9% for non-<it>P. falciparum</it>) and were similar to those for the CareStart Malaria™ test.</p> <p>Conclusions</p> <p>This new RDT performs similarly well as other commercially available tests (especially the CareStart Malaria™ test, used as comparator), and conforms to the World Health Organization’s recommendations for RDT performance. It is a good alternative tool for the diagnosis of malaria in endemic areas.</p>http://www.malariajournal.com/content/11/1/295 |
| spellingShingle | Chou Monidarin Kim Saorin Khim Nimol Chy Sophy Sum Sarorn Dourng Dany Canier Lydie Nguon Chea Ménard Didier Performance of “VIKIA Malaria Ag Pf/Pan” (IMACCESS®), a new malaria rapid diagnostic test for detection of symptomatic malaria infections Malaria Journal |
| title | Performance of “VIKIA Malaria Ag Pf/Pan” (IMACCESS®), a new malaria rapid diagnostic test for detection of symptomatic malaria infections |
| title_full | Performance of “VIKIA Malaria Ag Pf/Pan” (IMACCESS®), a new malaria rapid diagnostic test for detection of symptomatic malaria infections |
| title_fullStr | Performance of “VIKIA Malaria Ag Pf/Pan” (IMACCESS®), a new malaria rapid diagnostic test for detection of symptomatic malaria infections |
| title_full_unstemmed | Performance of “VIKIA Malaria Ag Pf/Pan” (IMACCESS®), a new malaria rapid diagnostic test for detection of symptomatic malaria infections |
| title_short | Performance of “VIKIA Malaria Ag Pf/Pan” (IMACCESS®), a new malaria rapid diagnostic test for detection of symptomatic malaria infections |
| title_sort | performance of vikia malaria ag pf pan imaccess r a new malaria rapid diagnostic test for detection of symptomatic malaria infections |
| url | http://www.malariajournal.com/content/11/1/295 |
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