A comprehensive next generation sequencing tissue assay for Asian-prevalent cancers—Analytical validation and performance evaluation with clinical samples

A comprehensive next generation sequencing tissue assay for Asian-prevalent cancers—Analytical validation and performance evaluation with clinical samples

Introduction: A well-validated diagnostic assay with curated biomarkers complements clinicopathological factors to facilitate early diagnosis and ensure timely treatment delivery. This study focuses on an Asian-centric cancer diagnostic assay designed and thoroughly validated against commercially av...

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Bibliographic Details
Main Authors: Cedric Chuan-Young Ng, Sandy Lim, Abner Herbert Lim, Nur Diyana Md Nasir, Jingxian Zhang, Vikneswari Rajasegaran, Jing Yi Lee, Jessica Sook Ting Kok, Aye Aye Thike, Johnathan Xiande Lim, Ruifen Weng, Sidney Yee, Yukti Choudhury, Jason Yongsheng Chan, Puay Hoon Tan, Min-Han Tan, Bin Tean Teh
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Molecular Biosciences
Subjects:
next-generation sequence (NGS)
hybrid capture
molecular diagnostics
asian cancers
genetic alteration
tissue assay
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2022.963243/full

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