Best Practices for Prognostic Evaluation of a Patient With Transthyretin Amyloid Cardiomyopathy

Transthyretin amyloid cardiomyopathy (ATTR-CM) has emerged as an increasingly identified etiology of heart failure. Fortunately, the disease now has an approved therapy, with many others under development. Assessment of prognosis in ATTR-CM is critical to inform patients about the disease course and...

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Main Authors: Kent Y. Feng, MD, Rahul S. Loungani, MD, Vishal N. Rao, MD, MPH, Chetan B. Patel, MD, Michel G. Khouri, MD, G. Michael Felker, MD, MHS, Adam D. DeVore, MD, MHS
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:JACC. CardioOncology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666087319300912
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author Kent Y. Feng, MD
Rahul S. Loungani, MD
Vishal N. Rao, MD, MPH
Chetan B. Patel, MD
Michel G. Khouri, MD
G. Michael Felker, MD, MHS
Adam D. DeVore, MD, MHS
author_facet Kent Y. Feng, MD
Rahul S. Loungani, MD
Vishal N. Rao, MD, MPH
Chetan B. Patel, MD
Michel G. Khouri, MD
G. Michael Felker, MD, MHS
Adam D. DeVore, MD, MHS
author_sort Kent Y. Feng, MD
collection DOAJ
description Transthyretin amyloid cardiomyopathy (ATTR-CM) has emerged as an increasingly identified etiology of heart failure. Fortunately, the disease now has an approved therapy, with many others under development. Assessment of prognosis in ATTR-CM is critical to inform patients about the disease course and guide clinical decisions. This review discusses the evidence behind clinical, biomarker, and imaging findings that inform prognosis in patients with ATTR-CM and can assist providers in the shared decision-making process during management of this disease.
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spelling doaj.art-01dc914b21a34c549e940ecc676cd2b82022-12-22T03:00:55ZengElsevierJACC. CardioOncology2666-08732019-12-0112273279Best Practices for Prognostic Evaluation of a Patient With Transthyretin Amyloid CardiomyopathyKent Y. Feng, MD0Rahul S. Loungani, MD1Vishal N. Rao, MD, MPH2Chetan B. Patel, MD3Michel G. Khouri, MD4G. Michael Felker, MD, MHS5Adam D. DeVore, MD, MHS6Stanford Center for Clinical Research, Stanford University School of Medicine, Stanford, CaliforniaDivision of Cardiology, Department of Medicine, Duke University Medical Center, Durham, North CarolinaDivision of Cardiology, Department of Medicine, Duke University Medical Center, Durham, North CarolinaDivision of Cardiology, Department of Medicine, Duke University Medical Center, Durham, North Carolina; Duke Clinical Research Institute, Durham, North CarolinaDivision of Cardiology, Department of Medicine, Duke University Medical Center, Durham, North Carolina; Duke Clinical Research Institute, Durham, North CarolinaDivision of Cardiology, Department of Medicine, Duke University Medical Center, Durham, North Carolina; Duke Clinical Research Institute, Durham, North CarolinaDivision of Cardiology, Department of Medicine, Duke University Medical Center, Durham, North Carolina; Duke Clinical Research Institute, Durham, North Carolina; Address for correspondence: Dr. Adam D. DeVore, Duke Clinical Research Institute, 200 Morris Street, #6318, Durham, North Carolina 27701.Transthyretin amyloid cardiomyopathy (ATTR-CM) has emerged as an increasingly identified etiology of heart failure. Fortunately, the disease now has an approved therapy, with many others under development. Assessment of prognosis in ATTR-CM is critical to inform patients about the disease course and guide clinical decisions. This review discusses the evidence behind clinical, biomarker, and imaging findings that inform prognosis in patients with ATTR-CM and can assist providers in the shared decision-making process during management of this disease.http://www.sciencedirect.com/science/article/pii/S2666087319300912amyloidosisbiomarkerscardiac magnetic resonancecardiomyopathyechocardiographynuclear imaging
spellingShingle Kent Y. Feng, MD
Rahul S. Loungani, MD
Vishal N. Rao, MD, MPH
Chetan B. Patel, MD
Michel G. Khouri, MD
G. Michael Felker, MD, MHS
Adam D. DeVore, MD, MHS
Best Practices for Prognostic Evaluation of a Patient With Transthyretin Amyloid Cardiomyopathy
JACC. CardioOncology
amyloidosis
biomarkers
cardiac magnetic resonance
cardiomyopathy
echocardiography
nuclear imaging
title Best Practices for Prognostic Evaluation of a Patient With Transthyretin Amyloid Cardiomyopathy
title_full Best Practices for Prognostic Evaluation of a Patient With Transthyretin Amyloid Cardiomyopathy
title_fullStr Best Practices for Prognostic Evaluation of a Patient With Transthyretin Amyloid Cardiomyopathy
title_full_unstemmed Best Practices for Prognostic Evaluation of a Patient With Transthyretin Amyloid Cardiomyopathy
title_short Best Practices for Prognostic Evaluation of a Patient With Transthyretin Amyloid Cardiomyopathy
title_sort best practices for prognostic evaluation of a patient with transthyretin amyloid cardiomyopathy
topic amyloidosis
biomarkers
cardiac magnetic resonance
cardiomyopathy
echocardiography
nuclear imaging
url http://www.sciencedirect.com/science/article/pii/S2666087319300912
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