Adaptative Up-Regulation of PRX2 and PRX5 Expression Characterizes Brain from a Mouse Model of Chorea-Acanthocytosis

Adaptative Up-Regulation of PRX2 and PRX5 Expression Characterizes Brain from a Mouse Model of Chorea-Acanthocytosis

The peroxiredoxins (PRXs) constitute a ubiquitous antioxidant. Growing evidence in neurodegenerative disorders such as Parkinson’s disease (PD) or Alzheimer’s disease (AD) has highlighted a crucial role for PRXs against neuro-oxidation. Chorea-acanthocytosis/<i>Vps13A</i> disease (ChAc)...

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Bibliographic Details
Main Authors:	Enrica Federti, Alessandro Matte, Veronica Riccardi, Kevin Peikert, Seth L. Alper, Adrian Danek, Ruth H. Walker, Angela Siciliano, Iana Iatcenko, Andreas Hermann, Lucia De Franceschi
Format:	Article
Language:	English
Published:	MDPI AG 2021-12-01
Series:	Antioxidants
Subjects:	peroxiredoxin 2 peroxiredoxin 5 neuroinflammation chorea-acanthocytosis nilotinib Lyn
Online Access:	https://www.mdpi.com/2076-3921/11/1/76

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