The diagnostic value of combined dynamic contrast-enhanced MRI (DCE-MRI) and diffusion-weighted imaging (DWI) in characterization of parotid gland tumors
Abstract Background MRI is considered to be the imaging modality of choice in preoperative diagnosis of parotid gland tumors and differentiating benign from malignant ones. Recently, functional MR imaging sequences including dynamic contrast-enhanced magnetic resonance imaging (DCE- MRI) and diffusi...
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| Format: | Article |
| Language: | English |
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SpringerOpen
2020-07-01
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| Series: | The Egyptian Journal of Radiology and Nuclear Medicine |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s43055-020-00237-8 |
| _version_ | 1819168202580557824 |
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| author | Mohamed Ali EL-Adalany Amany Ezzat Mohamed Mousa Dina EL-Metwally |
| author_facet | Mohamed Ali EL-Adalany Amany Ezzat Mohamed Mousa Dina EL-Metwally |
| author_sort | Mohamed Ali EL-Adalany |
| collection | DOAJ |
| description | Abstract Background MRI is considered to be the imaging modality of choice in preoperative diagnosis of parotid gland tumors and differentiating benign from malignant ones. Recently, functional MR imaging sequences including dynamic contrast-enhanced magnetic resonance imaging (DCE- MRI) and diffusion-weighted imaging (DWI) have significantly contributed to the diagnosis of head and neck masses. The purpose of this study was to evaluate the diagnostic value of combined DCE-MRI and DWI in characterization of parotid gland tumors. Results There was significant difference between benign and malignant parotid gland tumors as regard the type of time intensity curve (TIC) (P < 0.001). There was significant difference between pleomorphic adenoma (PMA) and malignant parotid gland tumors (MT) as regard mean ADC value (P = 0.046) and TTP (P = 0.002). There was no significant difference between Warthin’s tumor (WT) and malignant parotid gland tumors as regard the ADC value and TTP (P > 0.5); on the other hand, WT usually have high WR when compared with MT (P = 0.004). Combined use of DCE-MRI and DWI had 100% sensitivity, 90.5% specificity, and 93.3% accuracy in differentiating benign from malignant parotid gland tumors. Conclusion Combined use of DCE-MRI and DWI could result in high sensitivity, specificity, and diagnostic accuracy in characterization of parotid gland tumors. |
| first_indexed | 2024-12-22T18:59:52Z |
| format | Article |
| id | doaj.art-01ea980a721b4fe9a95b194703117edc |
| institution | Directory Open Access Journal |
| issn | 2090-4762 |
| language | English |
| last_indexed | 2024-12-22T18:59:52Z |
| publishDate | 2020-07-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | The Egyptian Journal of Radiology and Nuclear Medicine |
| spelling | doaj.art-01ea980a721b4fe9a95b194703117edc2022-12-21T18:15:59ZengSpringerOpenThe Egyptian Journal of Radiology and Nuclear Medicine2090-47622020-07-0151111010.1186/s43055-020-00237-8The diagnostic value of combined dynamic contrast-enhanced MRI (DCE-MRI) and diffusion-weighted imaging (DWI) in characterization of parotid gland tumorsMohamed Ali EL-Adalany0Amany Ezzat Mohamed Mousa1Dina EL-Metwally2Department of Diagnostic Radiology, Faculty of Medicine, Mansoura universityDepartment of Diagnostic Radiology, Faculty of Medicine, Mansoura universityDepartment of Diagnostic Radiology, Faculty of Medicine, Mansoura universityAbstract Background MRI is considered to be the imaging modality of choice in preoperative diagnosis of parotid gland tumors and differentiating benign from malignant ones. Recently, functional MR imaging sequences including dynamic contrast-enhanced magnetic resonance imaging (DCE- MRI) and diffusion-weighted imaging (DWI) have significantly contributed to the diagnosis of head and neck masses. The purpose of this study was to evaluate the diagnostic value of combined DCE-MRI and DWI in characterization of parotid gland tumors. Results There was significant difference between benign and malignant parotid gland tumors as regard the type of time intensity curve (TIC) (P < 0.001). There was significant difference between pleomorphic adenoma (PMA) and malignant parotid gland tumors (MT) as regard mean ADC value (P = 0.046) and TTP (P = 0.002). There was no significant difference between Warthin’s tumor (WT) and malignant parotid gland tumors as regard the ADC value and TTP (P > 0.5); on the other hand, WT usually have high WR when compared with MT (P = 0.004). Combined use of DCE-MRI and DWI had 100% sensitivity, 90.5% specificity, and 93.3% accuracy in differentiating benign from malignant parotid gland tumors. Conclusion Combined use of DCE-MRI and DWI could result in high sensitivity, specificity, and diagnostic accuracy in characterization of parotid gland tumors.http://link.springer.com/article/10.1186/s43055-020-00237-8Parotid glandMRIDWIDCE-MRI |
| spellingShingle | Mohamed Ali EL-Adalany Amany Ezzat Mohamed Mousa Dina EL-Metwally The diagnostic value of combined dynamic contrast-enhanced MRI (DCE-MRI) and diffusion-weighted imaging (DWI) in characterization of parotid gland tumors The Egyptian Journal of Radiology and Nuclear Medicine Parotid gland MRI DWI DCE-MRI |
| title | The diagnostic value of combined dynamic contrast-enhanced MRI (DCE-MRI) and diffusion-weighted imaging (DWI) in characterization of parotid gland tumors |
| title_full | The diagnostic value of combined dynamic contrast-enhanced MRI (DCE-MRI) and diffusion-weighted imaging (DWI) in characterization of parotid gland tumors |
| title_fullStr | The diagnostic value of combined dynamic contrast-enhanced MRI (DCE-MRI) and diffusion-weighted imaging (DWI) in characterization of parotid gland tumors |
| title_full_unstemmed | The diagnostic value of combined dynamic contrast-enhanced MRI (DCE-MRI) and diffusion-weighted imaging (DWI) in characterization of parotid gland tumors |
| title_short | The diagnostic value of combined dynamic contrast-enhanced MRI (DCE-MRI) and diffusion-weighted imaging (DWI) in characterization of parotid gland tumors |
| title_sort | diagnostic value of combined dynamic contrast enhanced mri dce mri and diffusion weighted imaging dwi in characterization of parotid gland tumors |
| topic | Parotid gland MRI DWI DCE-MRI |
| url | http://link.springer.com/article/10.1186/s43055-020-00237-8 |
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