Targeting CD89 on tumor-associated macrophages overcomes resistance to immune checkpoint blockade

Targeting CD89 on tumor-associated macrophages overcomes resistance to immune checkpoint blockade

Background Despite the survival benefits observed with immune checkpoint blockade (ICB) treatment—programmed cell death-1/programmed cell death ligand-1 (PD-1/PD-L1), many patients with cancer have not benefited from these agents because of impaired antigen presentation and other resistance mechanis...

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Bibliographic Details
Main Authors:	Zhaohua Zhu, Yan Feng, Bingyu Li, Hua Gu, LiJun Xu, Chenyu Pi, Fei Tao, Kun Xie, Xiaoqing Xu, Yanxin Yin, Jianmin Fang
Format:	Article
Language:	English
Published:	BMJ Publishing Group 2022-12-01
Series:	Journal for ImmunoTherapy of Cancer
Online Access:	https://jitc.bmj.com/content/10/12/e005447.full

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